Astros Roster & Staff
Transactions
| Date | Transaction |
| 05/31/25 | Houston Astros placed CF Chas McCormick on the 10-day injured list retroactive to May 30, 2025. Left oblique strain. |
| 05/31/25 | Houston Astros signed free agent RHP Cristhopher Mejias to a minor league contract. |
| 05/31/25 | Houston Astros recalled SS Shay Whitcomb from Sugar Land Space Cowboys. |
| 05/29/25 | Houston Astros sent RF Pedro León on a rehab assignment to Sugar Land Space Cowboys. |
| 05/29/25 | Houston Astros sent RF Pedro León on a rehab assignment to Sugar Land Space Cowboys. |
| 05/28/25 | Houston Astros signed free agent IF Cliuver Puello to a minor league contract. |
| 05/24/25 | Houston Astros signed free agent LHP Matt Mikulski to a minor league contract. |
| 05/22/25 | Houston Astros placed RHP Ronel Blanco on the 15-day injured list retroactive to May 20, 2025. Right elbow inflammation. |
| 05/22/25 | Houston Astros sent RF Pedro León on a rehab assignment to FCL Astros. |
| 05/22/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 05/21/25 | RHP Tayler Scott elected free agency. |
| 05/21/25 | Houston Astros activated RHP Forrest Whitley from the 15-day injured list. |
| 05/21/25 | Houston Astros optioned LHP Brandon Walter to Sugar Land Space Cowboys. |
| 05/20/25 | Houston Astros signed free agent RF Greg Jones to a minor league contract. |
| 05/20/25 | Houston Astros transferred RHP Hayden Wesneski from the 15-day injured list to the 60-day injured list. |
| 05/20/25 | Houston Astros signed free agent SS Edwin Díaz to a minor league contract. |
| 05/20/25 | Houston Astros signed 3B Bryce Willits. |
| 05/20/25 | Houston Astros optioned LHP Colton Gordon to Sugar Land Space Cowboys. |
| 05/20/25 | Houston Astros selected the contract of LHP Brandon Walter from Sugar Land Space Cowboys. |
| 05/18/25 | Houston Astros claimed RHP Jason Alexander off waivers from Athletics. |
| 05/15/25 | Houston Astros signed free agent C Hayden Travinski to a minor league contract. |
| 05/15/25 | Houston Astros traded RHP Miguel Castro to Chicago White Sox for cash. |
| 05/14/25 | Houston Astros designated RHP Tayler Scott for assignment. |
| 05/14/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 05/13/25 | Houston Astros sent RHP Forrest Whitley on a rehab assignment to Sugar Land Space Cowboys. |
| 05/11/25 | Houston Astros activated RHP Shawn Dubin from the 15-day injured list. |
| 05/11/25 | Houston Astros optioned RHP Logan VanWey to Sugar Land Space Cowboys. |
| 05/09/25 | Houston Astros placed RHP Hayden Wesneski on the 15-day injured list retroactive to May 7, 2025. Right elbow discomfort. |
| 05/09/25 | Houston Astros recalled RHP Logan VanWey from Sugar Land Space Cowboys. |
| 05/05/25 | Houston Astros signed free agent OF Edwilmin Matos to a minor league contract. |
| 05/05/25 | Houston Astros signed free agent RHP Cody Tucker to a minor league contract. |
| 05/05/25 | Houston Astros placed LF Yordan Alvarez on the 10-day injured list retroactive to May 3, 2025. Right hand inflammation. |
| 05/05/25 | Houston Astros recalled C César Salazar from Sugar Land Space Cowboys. |
| 05/04/25 | Houston Astros activated RHP Lance McCullers Jr. from the 15-day injured list. |
| 05/04/25 | Houston Astros optioned RHP Logan VanWey to Sugar Land Space Cowboys. |
| 05/02/25 | Houston Astros activated RHP Bryan Abreu from the paternity list. |
| 05/02/25 | Houston Astros signed free agent RHP Tyler Ras to a minor league contract. |
| 05/01/25 | Houston Astros optioned RHP AJ Blubaugh to Sugar Land Space Cowboys. |