Astros Roster & Staff
Transactions
| Date | Transaction |
| 09/30/25 | Houston Astros signed free agent RHP Vismar Dagnino to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent IF Oscar Rivas to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent RHP Juan Ramirez to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent OF Yuaxander Silveira to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent RHP Victor Vizcaya to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent RHP Samil Valdivieso to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent IF Noel Brito to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent RHP David Colina to a minor league contract. |
| 09/30/25 | Houston Astros signed free agent RHP Adrianyer Lopez to a minor league contract. |
| 09/30/25 | Houston Astros sent RHP Nick Hernandez outright to Sugar Land Space Cowboys. |
| 09/29/25 | Houston Astros activated CF Jake Meyers from the 10-day injured list. |
| 09/29/25 | Houston Astros activated RHP Spencer Arrighetti from the 15-day injured list. |
| 09/29/25 | Houston Astros activated LF Yordan Alvarez from the 10-day injured list. |
| 09/29/25 | Houston Astros activated LHP Josh Hader from the 15-day injured list. |
| 09/29/25 | Houston Astros activated LHP Bennett Sousa from the 15-day injured list. |
| 09/29/25 | Houston Astros activated SS Jeremy Peña from the 10-day injured list. |
| 09/29/25 | Houston Astros recalled CF Kenedy Corona from Sugar Land Space Cowboys. |
| 09/29/25 | Houston Astros recalled LF Chas McCormick from Sugar Land Space Cowboys. |
| 09/29/25 | Houston Astros recalled LF Shay Whitcomb from Sugar Land Space Cowboys. |
| 09/29/25 | Houston Astros recalled RHP Logan VanWey from Sugar Land Space Cowboys. |
| 09/29/25 | Houston Astros recalled C César Salazar from Sugar Land Space Cowboys. |
| 09/28/25 | Houston Astros placed SS Jeremy Peña on the 10-day injured list retroactive to September 25, 2025. Left oblique strain. |
| 09/28/25 | Houston Astros recalled LF Jacob Melton from Sugar Land Space Cowboys. |
| 09/27/25 | Houston Astros placed CF Jake Meyers on the 10-day injured list retroactive to September 25, 2025. Right calf soreness. |
| 09/27/25 | Houston Astros activated SS Brice Matthews. |
| 09/27/25 | Houston Astros activated RHP Lance McCullers Jr. from the 15-day injured list. |
| 09/27/25 | Houston Astros designated RHP Nick Hernandez for assignment. |
| 09/27/25 | Houston Astros recalled SS Brice Matthews from Sugar Land Space Cowboys. |
| 09/19/25 | Houston Astros placed LF Yordan Alvarez on the 10-day injured list retroactive to September 16, 2025. Left ankle sprain. |
| 09/19/25 | Houston Astros sent LF Zach Dezenzo on a rehab assignment to Sugar Land Space Cowboys. |
| 09/19/25 | Houston Astros transferred RHP Kaleb Ort from the 15-day injured list to the 60-day injured list. Right elbow inflammation. |
| 09/19/25 | Houston Astros activated 3B Isaac Paredes from the 60-day injured list. |
| 09/16/25 | C Victor Caratini changed number to 17. |
| 09/16/25 | LF Jose Altuve changed number to 27. |
| 09/16/25 | SS Jeremy Peña changed number to 3. |
| 09/16/25 | 2B Mauricio Dubón changed number to 14. |
| 09/16/25 | SS Carlos Correa changed number to 1. |
| 09/16/25 | LF Yordan Alvarez changed number to 44. |
| 09/15/25 | LF Yordan Alvarez changed number to 21. |
| 09/15/25 | LF Jose Altuve changed number to 21. |
| 09/15/25 | C Victor Caratini changed number to 21. |
| 09/15/25 | SS Carlos Correa changed number to 21. |
| 09/15/25 | 2B Mauricio Dubón changed number to 21. |
| 09/15/25 | SS Jeremy Peña changed number to 21. |
| 09/12/25 | Houston Astros placed RHP Lance McCullers Jr. on the 15-day injured list. Right hand soreness. |
| 09/12/25 | Houston Astros transferred RHP Luis Garcia from the 15-day injured list to the 60-day injured list. Right elbow discomfort. |
| 09/12/25 | Houston Astros selected the contract of CF Zach Cole from Sugar Land Space Cowboys. |
| 09/12/25 | Houston Astros optioned C César Salazar to Sugar Land Space Cowboys. |
| 09/12/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 09/10/25 | Houston Astros placed RHP Luis Garcia on the 15-day injured list. Right elbow discomfort. |
| 09/10/25 | Houston Astros recalled RHP Nick Hernandez from Sugar Land Space Cowboys. |
| 09/09/25 | Houston Astros optioned RHP Logan VanWey to Sugar Land Space Cowboys. |
| 09/09/25 | Houston Astros recalled RHP J.P. France from Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros activated CF Jake Meyers from the 10-day injured list. |
| 09/06/25 | Houston Astros optioned LF Jacob Melton to Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros optioned LHP Colton Gordon to Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros recalled RHP Logan VanWey from Sugar Land Space Cowboys. |
| 09/05/25 | Houston Astros placed RHP Kaleb Ort on the 15-day injured list. Right elbow inflammation. |
| 09/05/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 09/04/25 | Houston Astros sent RF Pedro León on a rehab assignment to Sugar Land Space Cowboys. |
| 09/03/25 | Houston Astros placed RHP Spencer Arrighetti on the 15-day injured list retroactive to August 31, 2025. Right elbow inflammation. |
| 09/03/25 | Houston Astros activated C Victor Caratini from the 7-day injured list. |
| 09/03/25 | Houston Astros transferred LHP John Rooney from the 15-day injured list to the 60-day injured list. |
| 09/03/25 | Los Angeles Angels claimed 1B Logan Davidson off waivers from Houston Astros. |
| 09/03/25 | Houston Astros optioned LF Chas McCormick to Sugar Land Space Cowboys. |
| 09/03/25 | Houston Astros selected the contract of RHP Jayden Murray from Sugar Land Space Cowboys. |
| 09/01/25 | Houston Astros activated LF Taylor Trammell from the 10-day injured list. |
| 09/01/25 | Houston Astros activated RHP Luis Garcia from the 60-day injured list. |
| 09/01/25 | Houston Astros designated 1B Logan Davidson for assignment. |