| First Game | vs. Rockies | 3/31/98 |
| First Batter | Devon White | 3/31/98 |
| First Hit | Travis Lee, First Inning | 3/31/98 |
| First Run Scored/RBI | Travis Lee, Sixth Inning on a Home Run | 3/31/98 |
| First Pitch | Andy Benes | 3/31/98 |
| First Strikeout | by Andy Benes, Larry Walker | 3/31/98 |
| First Win | vs. Giants, 3-2 | 4/5/98 |
| First Loss | vs. Rockies, 9-2 | 3/31/98 |
| First Winning Pitcher | Andy Benes; vs. Giants | 4/5/98 |
| First Losing Pitcher | Andy Benes; vs. Rockies | 3/31/98 |
| First Road Win | at Dodgers, 3-0 | 4/8/98 |
| First Road Loss | at Dodgers, 9-1 | 4/7/98 |
| First Extra-Inning Win | at Marlins, 11 innings (4-3) | 4/25/98 |
| First Double | Chris Jones; vs. Rockies | 4/2/98 |
| First Triple | Brent Brede; vs. Giants | 4/3/98 |
| First Grand Slam | Matt Williams; at Cardinals | 4/14/98 |
| First Home Run By Pitcher | Andy Benes; at Padres | 4/10/98 |
| Two Home Runs in a Game | Matt Williams; at Marlins | 4/25/98 |
| First Inning Leadoff HR | Devon White; at Expos | 5/1/98 |
| First D-back HR Into Pool | Devon White; vs. Pirates | 5/16/98 |
| First Pinch-Hit HR | Tony Batista; at Cubs | 8/3/98 |
| First Complete Game | Brian Anderson; at Padres, 8.0 IP (Lost, 1-0) | 4/13/98 |
| First Complete Game Win | Andy Benes (9.0 IP); at Cardinals, 8-2 | 4/16/98 |
| First Shutout | Brian Anderson (8.0 IP), Felix Rodriguez (1.0 IP); at Dodgers | 4/8/98 |
| First Complete Game Shutout | vs. Chicago, 4-0; Omar Daal, four-hitter | 7/30/98 |
| First Perfect Game | at Atlanta, 2-0; Randy Johnson | 5/18/04 |
| First Save | Felix Rodriguez; vs. Giants | 4/5/98 |
| First Strike Out the Side | Willie Blair; at Expos | 5/3/98 |
| First D-back Error | Edwin Diaz; vs. Colorado | 4/1/98 |
| First Stolen Base | Travis Lee; vs. Rockies | 4/1/98 |
| First Steal of Home | Andy Fox; vs. Mets | 8/16/98 |
| First Hit by Pitch | Jay Bell; vs. Rockies | 4/2/98 |
| First Rainout | at Cardinals | 4/15/98 |
| First Ejection | Devon White; vs. Giants | 4/3/98 |
| First Roof Opening | 7:45 p.m.; vs. Rockies | 3/31/98 |
