Padres Roster & Staff
Transactions
| Date | Transaction |
| 03/17/25 | LHP Igor Gil assigned to San Diego Padres. |
| 03/17/25 | C Carlos Rodriguez assigned to San Diego Padres. |
| 03/17/25 | 2B Wyatt Hoffman assigned to San Diego Padres. |
| 03/17/25 | RHP Vicarte Domingo assigned to San Diego Padres. |
| 03/16/25 | RHP Jimmy Reyes assigned to San Diego Padres. |
| 03/16/25 | LHP Braian Salazar assigned to San Diego Padres. |
| 03/16/25 | OF Moisés Gómez assigned to San Diego Padres. |
| 03/15/25 | LHP Ruben Salinas assigned to San Diego Padres. |
| 03/14/25 | San Diego Padres signed free agent RHP Miguel Angel Ledesma to a minor league contract. |
| 03/13/25 | San Diego Padres optioned LHP Omar Cruz to El Paso Chihuahuas. |
| 03/13/25 | San Diego Padres optioned LHP Tom Cosgrove to El Paso Chihuahuas. |
| 03/11/25 | RHP Maikel Miralles assigned to San Diego Padres. |
| 03/11/25 | RHP Johan Moreno assigned to San Diego Padres. |
| 03/11/25 | LHP Luis Gutierrez assigned to San Diego Padres. |
| 03/10/25 | C Alcides Hernandez assigned to San Diego Padres. |
| 03/09/25 | RHP Carson Swilling assigned to San Diego Padres. |
| 03/09/25 | San Diego Padres optioned RHP Ryan Bergert to El Paso Chihuahuas. |
| 03/08/25 | C Kaden Hollow assigned to San Diego Padres. |
| 03/08/25 | 2B Jose Iglesias assigned to San Diego Padres. |
| 03/07/25 | RHP Jared Kollar assigned to San Diego Padres. |
| 03/07/25 | 2B Ripken Reyes assigned to San Diego Padres. |
| 03/07/25 | San Diego Padres optioned RHP Henry Baez to El Paso Chihuahuas. |
| 03/06/25 | C Oswaldo Linares assigned to San Diego Padres. |
| 03/06/25 | RHP Kleiber Olmedo assigned to San Diego Padres. |
| 03/06/25 | 2B Chase Valentine assigned to San Diego Padres. |
| 03/06/25 | RHP Miguel Valdez assigned to San Diego Padres. |
| 03/05/25 | LHP Wes Benjamin assigned to San Diego Padres. |
| 03/05/25 | RHP Eric Yost assigned to San Diego Padres. |
| 03/05/25 | C Yoiber Ocopio assigned to San Diego Padres. |
| 03/04/25 | RHP Alejandro Lugo assigned to San Diego Padres. |
| 03/04/25 | C Brendan Durfee assigned to San Diego Padres. |
| 03/04/25 | C Cody Roberts assigned to San Diego Padres. |
| 03/04/25 | LHP Jackson Wolf assigned to San Diego Padres. |
| 03/04/25 | C Addison Kopack assigned to San Diego Padres. |
| 03/04/25 | 2B Marcos Castañon assigned to San Diego Padres. |
| 03/04/25 | RHP Bernard Jose assigned to San Diego Padres. |
| 03/04/25 | 2B Marcos Castañon roster status changed by San Diego Padres. |
| 03/02/25 | RHP Jose Luis Reyes assigned to San Diego Padres. |
| 03/02/25 | LHP Harry Gustin assigned to San Diego Padres. |
| 03/02/25 | RHP Josh Mallitz assigned to San Diego Padres. |
| 03/01/25 | RHP Tyler Morgan assigned to San Diego Padres. |
| 03/01/25 | C Colton Vincent assigned to San Diego Padres. |