Padres Roster & Staff
Transactions
| Date | Transaction |
| 05/17/26 | San Diego Padres sent RHP Jhony Brito on a rehab assignment to San Antonio Missions. |
| 05/17/26 | San Diego Padres recalled RHP Lucas Giolito from San Antonio Missions. |
| 05/17/26 | San Diego Padres optioned RHP Alek Jacob to El Paso Chihuahuas. |
| 05/15/26 | San Diego Padres placed RHP Matt Waldron on the 15-day injured list. Right brachialis muscle injury. |
| 05/15/26 | San Diego Padres recalled RHP Alek Jacob from El Paso Chihuahuas. |
| 05/07/26 | San Diego Padres sent RHP Jhony Brito on a rehab assignment to ACL Padres. |
| 05/07/26 | San Diego Padres transferred RHP Joe Musgrove from the 15-day injured list to the 60-day injured list. |
| 05/07/26 | San Diego Padres placed C Luis Campusano on the 10-day injured list. Left toe fracture. |
| 05/07/26 | San Diego Padres activated 3B Will Wagner from the 10-day injured list. |
| 05/07/26 | San Diego Padres selected the contract of C Rodolfo Durán from El Paso Chihuahuas. |
| 05/07/26 | San Diego Padres optioned 3B Will Wagner to El Paso Chihuahuas. |
| 05/05/26 | San Diego Padres activated LHP Yuki Matsui from the 15-day injured list. |
| 05/05/26 | San Diego Padres placed 2B Jake Cronenworth on the 7-day injured list. Concussion symptoms. |
| 05/05/26 | San Diego Padres recalled 3B Sung-Mun Song from El Paso Chihuahuas. |
| 05/05/26 | San Diego Padres optioned LHP Kyle Hart to El Paso Chihuahuas. |
| 05/03/26 | San Diego Padres activated RHP Griffin Canning from the 15-day injured list. |
| 05/03/26 | San Diego Padres placed RHP Germán Márquez on the 15-day injured list retroactive to May 2, 2026. Forearm nerve inflammation. |
| 05/01/26 | San Diego Padres sent 3B Will Wagner on a rehab assignment to El Paso Chihuahuas. |
| 05/01/26 | San Diego Padres activated RHP Jeremiah Estrada from the 15-day injured list. |