Padres Roster & Staff
Transactions
| Date | Transaction |
| 03/29/11 | San Diego Padres placed RHP Mat Latos on the 15-day disabled list retroactive to March 22, 2011. Strained right shoulder. |
| 03/29/11 | San Diego Padres placed LHP Joe Thatcher on the 15-day disabled list retroactive to March 22, 2011. Strained left shoulder. |
| 03/29/11 | Samuel Deduno roster status changed by San Diego Padres. |
| 03/29/11 | San Diego Padres recalled Samuel Deduno from Tucson Padres. |
| 03/29/11 | Kyle Blanks roster status changed by San Diego Padres. |
| 03/29/11 | San Diego Padres placed 3B Jarrett Hoffpauir on the 15-day disabled list retroactive to March 22, 2011. Strained right quadriceps. |
| 03/29/11 | 1B Cody Decker assigned to San Diego Padres. |
| 03/29/11 | C Rocky Gale assigned to San Diego Padres. |
| 03/29/11 | 3B Edinson Rincon assigned to San Diego Padres. |
| 03/28/11 | San Diego Padres placed CF Eric Patterson on the 15-day disabled list retroactive to March 22, 2011. Strained left hamstring. |
| 03/28/11 | San Diego Padres recalled Cedric Hunter from Tucson Padres. |
| 03/28/11 | San Antonio Missions Traded RHP Erik Davis to Harrisburg Senators; Washington Nationals Traded 2B Alberto Gonzalez to San Diego Padres and San Diego Padres Traded cash to Washington Nationals. |
| 03/28/11 | Mike Baxter roster status changed by San Diego Padres. |
| 03/28/11 | San Diego Padres optioned Aaron Cunningham to Tucson Padres. |
| 03/28/11 | San Diego Padres released 2B Oscar Salazar. |
| 03/28/11 | San Diego Padres optioned Wade LeBlanc to Tucson Padres. |
| 03/28/11 | San Diego Padres optioned SS Everth Cabrera to Tucson Padres. |
| 03/28/11 | San Antonio Missions Traded RHP Erik Davis to Harrisburg Senators; Washington Nationals Traded 2B Alberto Gonzalez to San Diego Padres and San Diego Padres Traded cash to Washington Nationals. |
| 03/27/11 | 3B Jake Blackwood assigned to San Diego Padres. |
| 03/26/11 | RHP Scott Dohmann assigned to San Diego Padres. |
| 03/25/11 | OF Mykal Stokes assigned to San Diego Padres. |
| 03/25/11 | San Diego Padres released 3B Kevin Frandsen. |
| 03/25/11 | San Diego Padres released RHP Rod Scurry. |
| 03/24/11 | OF Jose Dore assigned to San Diego Padres. |
| 03/23/11 | IF Dean Anna assigned to San Diego Padres. |
| 03/23/11 | C Roman Ali Solis assigned to San Diego Padres. |
| 03/22/11 | 3B Jedd Gyorko assigned to San Diego Padres. |
| 03/22/11 | OF Sawyer Carroll assigned to San Diego Padres. |
| 03/21/11 | SS Drew Cumberland assigned to San Diego Padres. |
| 03/21/11 | OF Blake Tekotte assigned to San Diego Padres. |
| 03/21/11 | OF Jaff Decker assigned to San Diego Padres. |
| 03/20/11 | San Diego Padres claimed RHP Pat Neshek off waivers from Minnesota Twins. |
| 03/20/11 | San Diego Padres optioned Samuel Deduno to Tucson Padres. |
| 03/20/11 | San Diego Padres optioned CF Luis Durango to Tucson Padres. |
| 03/20/11 | C Griffin Benedict assigned to San Diego Padres. |
| 03/20/11 | 3B Vince Belnome assigned to San Diego Padres. |
| 03/20/11 | LHP Josh Spence assigned to San Diego Padres. |
| 03/20/11 | OF Dan Robertson assigned to San Diego Padres. |
| 03/19/11 | CF Rico Noel assigned to San Diego Padres. |
| 03/19/11 | Jesus Lopez loaned to Guerreros de Oaxaca from San Diego Padres. |
| 03/19/11 | OF Danny Payne assigned to San Diego Padres. |
| 03/18/11 | SS Beamer Weems assigned to San Diego Padres. |
| 03/18/11 | OF Bobby Kielty assigned to San Diego Padres. |
| 03/15/11 | RHP Aaron Breit assigned to San Diego Padres. |
| 03/15/11 | San Diego Padres optioned Cedric Hunter to Tucson Padres. |
| 03/15/11 | RHP Mike DeMark assigned to San Diego Padres. |
| 03/14/11 | George Kontos returned to Scranton/Wilkes-Barre Yankees from San Diego Padres. |
| 03/13/11 | RHP Mike Koplove assigned to San Diego Padres. |
| 03/13/11 | RHP Nick Vincent assigned to San Diego Padres. |
| 03/12/11 | San Diego Padres released RHP Christopher Rollins. |
| 03/12/11 | RHP Geoff Geary assigned to San Diego Padres. |
| 03/12/11 | RHP Jon Leicester assigned to San Diego Padres. |
| 03/11/11 | San Diego Padres optioned C Luis Martinez to Tucson Padres. |
| 03/11/11 | San Diego Padres optioned SS Jeudy Valdez to Lake Elsinore Storm. |
| 03/11/11 | San Diego Padres optioned Evan Scribner to Tucson Padres. |
| 03/11/11 | San Diego Padres optioned RHP Simon Castro to Tucson Padres. |
| 03/11/11 | San Diego Padres optioned RHP Jeremy Hefner to Tucson Padres. |
| 03/11/11 | San Diego Padres optioned Aaron Poreda to Tucson Padres. |
| 03/09/11 | CF Reymond Fuentes assigned to San Diego Padres. |
| 03/09/11 | SS Jonathan Galvez assigned to San Diego Padres. |
| 03/09/11 | CF Rymer Liriano assigned to San Diego Padres. |
| 03/09/11 | CF Everett Williams assigned to San Diego Padres. |
| 03/09/11 | 2B David Newhan assigned to San Diego Padres. |
| 03/09/11 | 1B Matt Clark assigned to San Diego Padres. |
| 03/09/11 | 3B Anthony Contreras assigned to San Diego Padres. |
| 03/09/11 | CF Luis Domoromo assigned to San Diego Padres. |
| 03/09/11 | C Emmanuel Quiles assigned to San Diego Padres. |
| 03/07/11 | San Diego Padres released C Gregg Zaun. |