White Sox Roster & Staff
Transactions
| Date | Transaction |
| 06/28/19 | Chicago White Sox placed SS Tim Anderson on the 10-day injured list retroactive to June 26, 2019. Sprained right ankle. |
| 06/28/19 | Chicago White Sox selected the contract of LHP Ross Detwiler from Charlotte Knights. |
| 06/28/19 | Chicago White Sox signed RHP Andrew Dalquist. |
| 06/28/19 | Chicago White Sox recalled Daniel Palka from Charlotte Knights. |
| 06/28/19 | Chicago White Sox designated 1B Yonder Alonso for assignment. |
| 06/28/19 | Chicago White Sox signed RHP Matthew Thompson. |
| 06/28/19 | Chicago White Sox signed 1B Andrew Vaughn. |
| 06/28/19 | Chicago White Sox signed free agent 3B Damek Tomscha to a minor league contract. |
| 06/28/19 | Chicago White Sox sent RHP Odrisamer Despaigne outright to Charlotte Knights. |
| 06/28/19 | Chicago White Sox signed RHP Caleb Freeman. |
| 06/26/19 | Chicago White Sox sent RHP Dylan Covey on a rehab assignment to Charlotte Knights. |
| 06/24/19 | Chicago White Sox activated CF Jon Jay from the 60-day injured list. |
| 06/24/19 | Chicago White Sox designated RHP Odrisamer Despaigne for assignment. |
| 06/20/19 | Chicago White Sox signed free agent LHP Hector Santiago to a minor league contract. |
| 06/19/19 | Chicago White Sox placed LHP Manny Banuelos on the 10-day injured list retroactive to June 16, 2019. Left shoulder inflammation. |
| 06/19/19 | Chicago White Sox recalled Carson Fulmer from Charlotte Knights. |
| 06/19/19 | Chicago White Sox signed free agent OF Jacob Scavuzzo to a minor league contract. |
| 06/18/19 | Chicago White Sox placed C Welington Castillo on the 10-day injured list retroactive to June 17, 2019. Strained left oblique. |
| 06/18/19 | Chicago White Sox activated LHP Jace Fry from the 10-day injured list. |
| 06/18/19 | Chicago White Sox selected the contract of Zack Collins from Charlotte Knights. |
| 06/17/19 | Chicago White Sox optioned RHP Thyago Vieira to Charlotte Knights. |
| 06/17/19 | Chicago White Sox signed RHP Hansen Butler. |
| 06/17/19 | Chicago White Sox signed LHP Sammy Peralta. |
| 06/15/19 | Cleveland Indians claimed RHP Jordan Stephens off waivers from Chicago White Sox. |
| 06/14/19 | Chicago White Sox signed RHP Nate Pawelczyk. |
| 06/14/19 | Chicago White Sox signed CF James Beard. |
| 06/14/19 | Chicago White Sox signed LHP Avery Weems. |
| 06/14/19 | Chicago White Sox signed RHP Karan Patel. |
| 06/14/19 | Chicago White Sox signed C Ivan Gonzalez. |
| 06/14/19 | Chicago White Sox signed RHP Tyson Messer. |
| 06/14/19 | Chicago White Sox signed LHP Dan Metzdorf. |
| 06/14/19 | Chicago White Sox signed C Victor Torres. |
| 06/14/19 | Chicago White Sox signed CF Misael Gonzalez Acosta. |
| 06/14/19 | Chicago White Sox signed RHP Cooper Bradford. |
| 06/14/19 | Chicago White Sox signed RHP McKinley Moore. |
| 06/14/19 | Chicago White Sox signed 3B DJ Gladney. |
| 06/14/19 | Chicago White Sox signed RHP Jeremiah Burke. |
| 06/14/19 | Chicago White Sox signed SS Joshua Rivera. |
| 06/14/19 | Chicago White Sox signed OF Cameron Simmons. |
| 06/14/19 | Chicago White Sox signed RHP Chase Solesky. |
| 06/14/19 | Chicago White Sox signed RHP Pauly Milto. |
| 06/14/19 | Chicago White Sox signed C Jakob Goldfarb. |
| 06/14/19 | Chicago White Sox signed RHP Justin Friedman. |
| 06/14/19 | Chicago White Sox signed 1B Tyler Osik. |
| 06/14/19 | Chicago White Sox signed RHP Kaleb Roper. |
| 06/14/19 | Chicago White Sox signed C Daniel Millwee. |
| 06/14/19 | Chicago White Sox signed RHP Connor Reich. |
| 06/14/19 | Chicago White Sox signed CF Jonathan Allen. |
| 06/14/19 | Chicago White Sox signed LHP Trey Jeans. |
| 06/14/19 | Chicago White Sox signed RHP Declan Cronin. |
| 06/14/19 | Chicago White Sox signed LHP Garvin Alston. |
| 06/14/19 | Chicago White Sox signed 2B Tom Archer. |
| 06/14/19 | Chicago White Sox signed RHP Nick Silva. |
| 06/14/19 | Chicago White Sox signed free agent RHP Allen Beer to a minor league contract. |
| 06/14/19 | Chicago White Sox signed free agent RHP Vladimir Nunez to a minor league contract. |
| 06/10/19 | Chicago White Sox selected the contract of RHP Odrisamer Despaigne from Charlotte Knights. |
| 06/10/19 | Chicago White Sox released LF Nicky Delmonico. |
| 06/10/19 | Chicago White Sox placed LHP Jace Fry on the 10-day injured list retroactive to June 8, 2019. Left shoulder soreness. |
| 06/09/19 | Chicago White Sox recalled Thyago Vieira from Charlotte Knights. |
| 06/09/19 | Chicago White Sox placed RHP Dylan Covey on the 10-day injured list retroactive to June 6, 2019. Right shoulder inflammation. |
| 06/07/19 | Chicago White Sox optioned RHP Jimmy Cordero to Charlotte Knights. |
| 06/07/19 | Chicago White Sox claimed RHP Jimmy Cordero off waivers from Seattle Mariners. |
| 06/07/19 | Chicago White Sox sent OF Jon Jay on a rehab assignment to Charlotte Knights. |
| 06/07/19 | Chicago White Sox transferred LHP Carlos Rodon from the 10-day injured list to the 60-day injured list. Left elbow inflammation. |
| 06/03/19 | Chicago White Sox sent OF Jon Jay on a rehab assignment to Birmingham Barons. |
| 06/01/19 | Chicago White Sox activated C Welington Castillo from the 7-day injured list. |
| 06/01/19 | Chicago White Sox optioned C Seby Zavala to Charlotte Knights. |