White Sox Roster & Staff
Transactions
| Date | Transaction |
| 04/29/26 | Chicago White Sox placed RF Everson Pereira on the 10-day injured list. Right pectoral strain. |
| 04/29/26 | Chicago White Sox selected the contract of RF Jarred Kelenic from Charlotte Knights. |
| 04/28/26 | Chicago White Sox sent RHP Jonathan Cannon on a rehab assignment to Charlotte Knights. |
| 04/28/26 | Chicago Cubs claimed LHP Doug Nikhazy off waivers from Chicago White Sox. |
| 04/27/26 | C Reese McGuire elected free agency. |
| 04/27/26 | Chicago White Sox signed free agent RHP Lucas Sims to a minor league contract. |
| 04/27/26 | Chicago White Sox activated LF Austin Hays from the 10-day injured list. |
| 04/27/26 | Chicago White Sox placed LF Tanner Murray on the 10-day injured list. Left shoulder dislocation. |
| 04/27/26 | Chicago White Sox sent C Reese McGuire outright to Charlotte Knights. |
| 04/25/26 | Chicago White Sox sent LF Austin Hays on a rehab assignment to Charlotte Knights. |
| 04/25/26 | Chicago White Sox sent LF Austin Hays on a rehab assignment to Charlotte Knights. |
| 04/25/26 | Chicago White Sox designated C Reese McGuire for assignment. |
| 04/25/26 | Chicago White Sox sent LHP Chris Murphy on a rehab assignment to Charlotte Knights. |
| 04/25/26 | Chicago White Sox selected the contract of C Drew Romo from Charlotte Knights. |
| 04/25/26 | Chicago White Sox sent RHP Lucas Sims outright to Charlotte Knights. |
| 04/23/26 | Chicago White Sox designated RHP Lucas Sims for assignment. |
| 04/23/26 | Chicago White Sox signed free agent RHP Choyce Diffey to a minor league contract. |
| 04/23/26 | Chicago White Sox selected the contract of RHP Tyler Davis from Charlotte Knights. |
| 04/19/26 | Chicago White Sox activated RHP Osvaldo Bido. |
| 04/19/26 | Chicago White Sox optioned LHP Doug Nikhazy to Charlotte Knights. |
| 04/18/26 | Chicago White Sox transferred RHP Prelander Berroa from the 15-day injured list to the 60-day injured list. Tommy John surgery recovery. |
| 04/18/26 | Chicago White Sox claimed RHP Osvaldo Bido off waivers from Atlanta Braves. |
| 04/18/26 | Houston Astros claimed LF Dustin Harris off waivers from Chicago White Sox. |
| 04/17/26 | Chicago White Sox recalled LHP Doug Nikhazy from Charlotte Knights. |
| 04/17/26 | Chicago White Sox optioned LHP Tyler Gilbert to Charlotte Knights. |
| 04/16/26 | 3B Miguel Vargas changed number to 20. |
| 04/16/26 | RHP Grant Taylor changed number to 31. |
| 04/16/26 | RHP Seranthony Domínguez changed number to 58. |
| 04/16/26 | RHP Jordan Leasure changed number to 49. |
| 04/16/26 | LHP Anthony Kay changed number to 18. |
| 04/16/26 | RHP Erick Fedde changed number to 47. |
| 04/16/26 | 2B Luisangel Acuña changed number to 0. |
| 04/16/26 | LF Andrew Benintendi changed number to 23. |
| 04/16/26 | RHP Jordan Hicks changed number to 44. |
| 04/16/26 | RHP Sean Burke changed number to 59. |
| 04/16/26 | RHP Lucas Sims changed number to 39. |
| 04/16/26 | LF Tristan Peters changed number to 29. |
| 04/16/26 | C Edgar Quero changed number to 26. |
| 04/16/26 | LHP Noah Schultz changed number to 22. |
| 04/16/26 | CF Everson Pereira changed number to 28. |
| 04/16/26 | LHP Sean Newcomb changed number to 15. |
| 04/16/26 | 2B Tanner Murray changed number to 41. |
| 04/16/26 | SS Chase Meidroth changed number to 10. |
| 04/16/26 | SS Colson Montgomery changed number to 12. |
| 04/16/26 | C Reese McGuire changed number to 30. |
| 04/16/26 | 3B Munetaka Murakami changed number to 5. |
| 04/16/26 | RHP Davis Martin changed number to 65. |
| 04/16/26 | LHP Bryan Hudson changed number to 60. |
| 04/16/26 | CF Derek Hill changed number to 25. |
| 04/16/26 | SS Sam Antonacci changed number to 17. |
| 04/16/26 | LHP Tyler Gilbert changed number to 40. |
| 04/15/26 | RHP Grant Taylor changed number to 42. |
| 04/15/26 | C Reese McGuire changed number to 42. |
| 04/15/26 | LHP Brandon Eisert changed number to 42. |
| 04/15/26 | LHP Bryan Hudson changed number to 42. |
| 04/15/26 | 3B Miguel Vargas changed number to 42. |
| 04/15/26 | Chicago White Sox designated LF Dustin Harris for assignment. |
| 04/15/26 | CF Derek Hill changed number to 42. |
| 04/15/26 | LHP Noah Schultz changed number to 42. |
| 04/15/26 | LF Andrew Benintendi changed number to 42. |
| 04/15/26 | 2B Luisangel Acuña changed number to 42. |
| 04/15/26 | LF Tristan Peters changed number to 42. |
| 04/15/26 | RHP Sean Burke changed number to 42. |
| 04/15/26 | CF Everson Pereira changed number to 42. |
| 04/15/26 | 3B Munetaka Murakami changed number to 42. |
| 04/15/26 | SS Chase Meidroth changed number to 42. |
| 04/15/26 | RHP Lucas Sims changed number to 42. |
| 04/15/26 | RHP Jordan Leasure changed number to 42. |
| 04/15/26 | LHP Sean Newcomb changed number to 42. |
| 04/15/26 | RHP Jordan Hicks changed number to 42. |
| 04/15/26 | LHP Anthony Kay changed number to 42. |
| 04/15/26 | C Edgar Quero changed number to 42. |
| 04/15/26 | RHP Seranthony Domínguez changed number to 42. |
| 04/15/26 | RHP Erick Fedde changed number to 42. |
| 04/15/26 | RHP Davis Martin changed number to 42. |
| 04/15/26 | SS Colson Montgomery changed number to 42. |
| 04/15/26 | LF Dustin Harris changed number to 42. |
| 04/15/26 | 2B Tanner Murray changed number to 42. |
| 04/15/26 | Chicago White Sox optioned LHP Brandon Eisert to Charlotte Knights. |
| 04/15/26 | Chicago White Sox recalled LHP Tyler Gilbert from Charlotte Knights. |
| 04/15/26 | Chicago White Sox selected the contract of SS Sam Antonacci from Charlotte Knights. |
| 04/14/26 | Chicago White Sox activated CF Everson Pereira from the 10-day injured list. |
| 04/14/26 | Chicago White Sox placed RHP Jonathan Cannon on the 15-day injured list retroactive to April 13, 2026. Right hip inflammation. |
| 04/14/26 | Chicago White Sox selected the contract of LHP Noah Schultz from Charlotte Knights. |
| 04/13/26 | Chicago White Sox traded 2B Lenyn Sosa to Toronto Blue Jays for OF Jordan Rich and Future Considerations. |
| 04/13/26 | Chicago White Sox traded 2B Lenyn Sosa to Toronto Blue Jays for OF Jordan Rich and Future Considerations. |
| 04/12/26 | Chicago White Sox sent CF Everson Pereira on a rehab assignment to Charlotte Knights. |
| 04/12/26 | Chicago White Sox recalled RHP Jonathan Cannon from Charlotte Knights. |
| 04/12/26 | Chicago White Sox optioned RHP Duncan Davitt to Charlotte Knights. |
| 04/09/26 | Chicago White Sox placed LHP Chris Murphy on the 15-day injured list retroactive to April 8, 2026. Left elbow impingement syndrome. |
| 04/09/26 | Chicago White Sox recalled RHP Duncan Davitt from Charlotte Knights. |
| 04/09/26 | Chicago White Sox optioned LHP Tyler Schweitzer to Charlotte Knights. |
| 04/09/26 | Chicago White Sox recalled LHP Brandon Eisert from Charlotte Knights. |
| 04/08/26 | Chicago White Sox transferred LF Brooks Baldwin from the 10-day injured list to the 60-day injured list. Right elbow sprain. |
| 04/08/26 | Chicago White Sox selected the contract of LHP Tyler Schweitzer from Charlotte Knights. |
| 04/08/26 | Chicago White Sox optioned RHP Shane Smith to Charlotte Knights. |
| 04/07/26 | Chicago White Sox placed LF Austin Hays on the 10-day injured list. Right hamstring strain. |
| 04/07/26 | Chicago White Sox placed RHP Mike Vasil on the 15-day injured list. Tommy John surgery recovery. |
| 04/07/26 | Chicago White Sox transferred RHP Mike Vasil from the 15-day injured list to the 60-day injured list. Tommy John surgery recovery. |
| 04/07/26 | Chicago White Sox selected the contract of LF Dustin Harris from Charlotte Knights. |
| 04/06/26 | Chicago White Sox optioned LHP Doug Nikhazy to Charlotte Knights. |
| 04/06/26 | Chicago White Sox claimed LHP Doug Nikhazy off waivers from Cleveland Guardians. |
| 04/05/26 | Chicago White Sox placed CF Everson Pereira on the 10-day injured list retroactive to April 2, 2026. Left ankle sprain. |
| 04/05/26 | Chicago White Sox recalled 2B Tanner Murray from Charlotte Knights. |
| 04/04/26 | RHP Jedixson Paez returned to Boston Red Sox from Chicago White Sox. |
| 04/02/26 | Chicago White Sox signed free agent RHP Drew Conover to a minor league contract. |
| 04/01/26 | Chicago White Sox signed free agent SS Efren Teran to a minor league contract. |
| 04/01/26 | Chicago White Sox designated RHP Jedixson Paez for assignment. |
| 04/01/26 | Chicago White Sox selected the contract of RHP Lucas Sims from Charlotte Knights. |