Red Sox Roster & Staff
Transactions
| Date | Transaction |
| 06/30/22 | Boston Red Sox sent LHP Chris Sale on a rehab assignment to Portland Sea Dogs. |
| 06/30/22 | Boston Red Sox activated 2B Jarren Duran from the restricted list. |
| 06/30/22 | Boston Red Sox sent LHP Chris Sale on a rehab assignment to Portland Sea Dogs. |
| 06/30/22 | Boston Red Sox designated RHP Silvino Bracho for assignment. |
| 06/30/22 | Boston Red Sox activated RHP Tanner Houck from the restricted list. |
| 06/30/22 | 2B Yolmer Sanchez returned to Worcester Red Sox from Boston Red Sox. |
| 06/28/22 | Boston Red Sox sent LHP Josh Taylor on a rehab assignment to Portland Sea Dogs. |
| 06/28/22 | Boston Red Sox optioned RHP Connor Seabold to Worcester Red Sox. |
| 06/28/22 | Boston Red Sox selected the contract of RHP Silvino Bracho from Worcester Red Sox. |
| 06/27/22 | Boston Red Sox activated 2B Yolmer Sanchez. |
| 06/27/22 | Boston Red Sox placed RHP Tanner Houck on the restricted list. |
| 06/27/22 | Boston Red Sox placed 2B Jarren Duran on the restricted list. |
| 06/27/22 | Boston Red Sox recalled RHP Connor Seabold from Worcester Red Sox. |
| 06/27/22 | Boston Red Sox selected the contract of 2B Yolmer Sanchez from Worcester Red Sox. |
| 06/25/22 | Boston Red Sox sent RHP James Norwood outright to Worcester Red Sox. |
| 06/24/22 | Boston Red Sox activated 3B Christian Arroyo. |
| 06/23/22 | Boston Red Sox optioned SS Jeter Downs to Worcester Red Sox. |
| 06/21/22 | Boston Red Sox sent LHP Josh Taylor on a rehab assignment to Worcester Red Sox. |
| 06/21/22 | Boston Red Sox sent 3B Christian Arroyo on a rehab assignment to Worcester Red Sox. |
| 06/20/22 | Boston Red Sox designated RHP James Norwood for assignment. |
| 06/20/22 | Boston Red Sox sent LHP Chris Sale on a rehab assignment to FCL Red Sox. |
| 06/20/22 | Boston Red Sox recalled SS Jeter Downs from Worcester Red Sox. |
| 06/19/22 | Boston Red Sox activated RHP James Norwood. |
| 06/19/22 | Boston Red Sox activated RHP James Norwood. |
| 06/19/22 | Boston Red Sox optioned RHP Kutter Crawford to Worcester Red Sox. |
| 06/18/22 | Philadelphia Phillies traded RHP James Norwood to Boston Red Sox for cash. |
| 06/15/22 | Boston Red Sox placed 3B Christian Arroyo on the 10-day injured list. |
| 06/15/22 | Boston Red Sox optioned RHP Phillips Valdez to Worcester Red Sox. |
| 06/15/22 | Baltimore Orioles claimed SS Jonathan Arauz off waivers from Boston Red Sox. |
| 06/15/22 | Boston Red Sox recalled RHP Josh Winckowski from Worcester Red Sox. |
| 06/15/22 | Boston Red Sox recalled 2B Jarren Duran from Worcester Red Sox. |
| 06/12/22 | Boston Red Sox placed RHP Nathan Eovaldi on the 15-day injured list retroactive to June 9, 2022. Low back inflammation. |
| 06/12/22 | Boston Red Sox recalled RHP Kutter Crawford from Worcester Red Sox. |
| 06/11/22 | Boston Red Sox signed free agent RHP Elvis Soto to a minor league contract. |
| 06/11/22 | Boston Red Sox signed free agent C Enmanuel Martinez to a minor league contract. |
| 06/10/22 | Boston Red Sox designated SS Jonathan Arauz for assignment. |
| 06/10/22 | Boston Red Sox placed RHP Garrett Whitlock on the 15-day injured list retroactive to June 9, 2022. Right hip inflammation. |
| 06/10/22 | Boston Red Sox recalled RHP Phillips Valdez from Worcester Red Sox. |
| 06/10/22 | Boston Red Sox selected the contract of 2B Rob Refsnyder and from Worcester Red Sox. |
| 06/09/22 | Boston Red Sox activated RHP Hansel Robles. |
| 06/09/22 | Boston Red Sox optioned RHP Phillips Valdez to Worcester Red Sox. |
| 06/08/22 | Boston Red Sox placed CF Enrique Hernandez on the 10-day injured list. Right hip flexor strain. |
| 06/08/22 | Boston Red Sox recalled SS Jonathan Arauz from Worcester Red Sox. |
| 06/07/22 | Boston Red Sox sent RHP Hansel Robles on a rehab assignment to Worcester Red Sox. |
| 06/06/22 | Boston Red Sox activated CF Jackie Bradley Jr. from the paternity list. |
| 06/06/22 | Boston Red Sox optioned 2B Jarren Duran to Worcester Red Sox. |
| 06/03/22 | Boston Red Sox placed CF Jackie Bradley Jr. on the paternity list. |
| 06/03/22 | Boston Red Sox recalled 2B Jarren Duran from Worcester Red Sox. |
| 06/01/22 | Boston Red Sox signed free agent RHP Luis Cohen to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent SS Yosander Asencio to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent RHP Darlyn De La Cruz to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent CF Natanael Yuten to a minor league contract. |
| 06/01/22 | Boston Red Sox placed RHP Matt Barnes on the 15-day injured list retroactive to May 31, 2022. Right shoulder inflammation. |
| 06/01/22 | Boston Red Sox signed free agent LHP Inmer Lobo to a minor league contract. |
| 06/01/22 | Boston Red Sox activated LHP Matt Strahm from the 10-day injured list. |
| 06/01/22 | Boston Red Sox signed free agent SS Fraymi De Leon to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent C Johanfran Garcia to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent SS Freili Encarnacion to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent RHP Willian Colmenares to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent SS Jancel Santana to a minor league contract. |
| 06/01/22 | Boston Red Sox signed free agent SS Franyer Noria to a minor league contract. |