White Sox Roster & Staff
Transactions
| Date | Transaction |
| 05/30/23 | Chicago White Sox traded CF Jake Marisnick to Detroit Tigers for cash. |
| 05/29/23 | Chicago White Sox placed RHP Jimmy Lambert on the 15-day injured list retroactive to May 28, 2023. Right ankle inflammation. |
| 05/29/23 | Chicago White Sox activated RHP Liam Hendriks from the 15-day injured list. |
| 05/28/23 | Chicago White Sox activated LF Eloy Jiménez from the 10-day injured list. |
| 05/28/23 | Chicago White Sox optioned CF Adam Haseley to Charlotte Knights. |
| 05/27/23 | Chicago White Sox sent SS Elvis Andrus on a rehab assignment to Charlotte Knights. |
| 05/27/23 | Chicago White Sox sent SS Elvis Andrus on a rehab assignment to Charlotte Knights. |
| 05/26/23 | Chicago White Sox sent CF Jake Marisnick outright to Charlotte Knights. |
| 05/25/23 | Chicago White Sox signed free agent RHP Josimar Cousin to a minor league contract. |
| 05/24/23 | Chicago White Sox signed free agent RHP Alexander Mateo to a minor league contract. |
| 05/24/23 | Chicago White Sox sent LF Eloy Jiménez on a rehab assignment to Birmingham Barons. |
| 05/22/23 | Chicago White Sox recalled RHP Jesse Scholtens from Charlotte Knights. |
| 05/21/23 | Chicago White Sox designated CF Jake Marisnick for assignment. |
| 05/21/23 | Chicago White Sox placed RHP Mike Clevinger on the 15-day injured list retroactive to May 18, 2023. Right wrist inflammation. |
| 05/21/23 | Chicago White Sox selected the contract of LF Clint Frazier from Charlotte Knights. |
| 05/17/23 | Chicago White Sox signed free agent RHP Pedro Redman to a minor league contract. |
| 05/16/23 | Chicago White Sox activated LHP Garrett Crochet from the 15-day injured list. |
| 05/16/23 | Chicago White Sox optioned RHP Nicholas Padilla to Charlotte Knights. |
| 05/14/23 | Chicago White Sox activated 3B Jake Burger from the 10-day injured list. |
| 05/14/23 | Chicago White Sox optioned C Carlos Pérez to Charlotte Knights. |
| 05/13/23 | Chicago White Sox activated 3B Romy González from the 10-day injured list. |
| 05/13/23 | Chicago White Sox placed SS Elvis Andrus on the 10-day injured list. Left oblique strain. |
| 05/12/23 | Chicago White Sox activated 2B Yoán Moncada from the 10-day injured list. |
| 05/12/23 | Chicago White Sox sent RHP Alex Colomé outright to Charlotte Knights. |
| 05/12/23 | Chicago White Sox optioned 3B Lenyn Sosa to Charlotte Knights. |
| 05/11/23 | Chicago White Sox sent 3B Jake Burger on a rehab assignment to Charlotte Knights. |
| 05/10/23 | Chicago White Sox designated RHP Alex Colomé for assignment. |
| 05/10/23 | Chicago White Sox placed CF Billy Hamilton on the 10-day injured list retroactive to May 7, 2023. Left hamstring strain. |
| 05/10/23 | Chicago White Sox recalled RHP Nicholas Padilla from Charlotte Knights. |
| 05/10/23 | Chicago White Sox selected the contract of CF Jake Marisnick from Charlotte Knights. |
| 05/09/23 | Chicago White Sox sent LHP Garrett Crochet on a rehab assignment to Charlotte Knights. |
| 05/08/23 | Chicago White Sox signed free agent RHP Bryan Shaw to a minor league contract. |
| 05/08/23 | Cincinnati Reds claimed RHP Franklin German off waivers from Chicago White Sox. |
| 05/07/23 | RHP Franklin German roster status changed by Chicago White Sox. |
| 05/07/23 | Chicago White Sox recalled C Carlos Pérez from Charlotte Knights. |
| 05/06/23 | Chicago White Sox placed LF Eloy Jiménez on the 10-day injured list. Appendectomy. |
| 05/06/23 | Chicago White Sox released LHP Jake Diekman. |
| 05/05/23 | Chicago White Sox activated RHP Joe Kelly from the paternity list. |
| 05/05/23 | Chicago White Sox sent RHP Liam Hendriks on a rehab assignment to Charlotte Knights. |
| 05/05/23 | Chicago White Sox sent 2B Yoán Moncada on a rehab assignment to Charlotte Knights. |
| 05/05/23 | Chicago White Sox sent 2B Yoán Moncada on a rehab assignment to Charlotte Knights. |
| 05/05/23 | Chicago White Sox optioned LHP Sammy Peralta to Charlotte Knights. |
| 05/04/23 | Chicago White Sox placed 3B Jake Burger on the 10-day injured list. Strained left oblique. |
| 05/04/23 | Chicago White Sox signed free agent RHP Reudis Diaz to a minor league contract. |
| 05/04/23 | Chicago White Sox recalled 3B Lenyn Sosa from Charlotte Knights. |
| 05/02/23 | Chicago White Sox designated LHP Jake Diekman for assignment. |
| 05/02/23 | Chicago White Sox placed 3B Romy González on the 10-day injured list retroactive to May 1, 2023. Right shoulder inflammation. |
| 05/02/23 | Chicago White Sox activated SS Tim Anderson from the 10-day injured list. |
| 05/02/23 | Chicago White Sox placed RHP Joe Kelly on the paternity list. |
| 05/02/23 | Chicago White Sox designated RHP Franklin German for assignment. |
| 05/02/23 | Chicago White Sox activated 2B Hanser Alberto from the 15-day injured list. |
| 05/02/23 | Chicago White Sox selected the contract of LHP Sammy Peralta from Charlotte Knights. |
| 05/02/23 | Chicago White Sox selected the contract of CF Billy Hamilton from Charlotte Knights. |
| 05/02/23 | Chicago White Sox optioned TWP Oscar Colás to Charlotte Knights. |
| 05/02/23 | Chicago White Sox selected the contract of RHP Alex Colomé from Charlotte Knights. |
| 05/01/23 | Chicago White Sox signed free agent RHP Luis Rodriguez to a minor league contract. |
| 05/01/23 | Chicago White Sox optioned 3B Lenyn Sosa to Charlotte Knights. |