Padres Roster & Staff
Transactions
| Date | Transaction |
| 11/30/25 | RF Nick Schnell roster status changed by San Diego Padres. |
| 11/30/25 | RF Nick Schnell roster status changed by San Diego Padres. |
| 11/30/25 | San Diego Padres signed free agent RF Nick Schnell to a minor league contract. |
| 11/26/25 | CF Jase Bowen roster status changed by San Diego Padres. |
| 11/26/25 | San Diego Padres signed free agent RHP Sean Boyle to a minor league contract. |
| 11/26/25 | San Diego Padres signed free agent CF Jase Bowen to a minor league contract. |
| 11/25/25 | RF Carlos Rodríguez roster status changed by San Diego Padres. |
| 11/25/25 | San Diego Padres signed free agent RF Carlos Rodríguez to a minor league contract. |
| 11/24/25 | San Diego Padres signed free agent RHP Randy Soto to a minor league contract. |
| 11/21/25 | RHP Sean Reynolds elected free agency. |
| 11/21/25 | LHP Omar Cruz elected free agency. |
| 11/19/25 | San Diego Padres signed free agent OF Albert Fabian to a minor league contract. |
| 11/18/25 | San Diego Padres selected the contract of RHP Garrett Hawkins from San Antonio Missions. |
| 11/18/25 | San Diego Padres selected the contract of RHP Miguel Mendez from San Antonio Missions. |
| 11/17/25 | San Diego Padres signed free agent LHP Kyle Hart. |
| 11/06/25 | San Diego Padres signed free agent OF Pablo Reyes to a minor league contract. |
| 11/06/25 | OF Pablo Reyes roster status changed by San Diego Padres. |
| 11/05/25 | San Diego Padres activated RHP Jhony Brito from the 60-day injured list. |
| 11/05/25 | San Diego Padres activated RHP Joe Musgrove from the 60-day injured list. |
| 11/05/25 | San Diego Padres activated RHP Jason Adam from the 60-day injured list. |
| 11/04/25 | RHP Robert Suarez elected free agency. |
| 11/04/25 | C Elias Díaz elected free agency. |
| 11/04/25 | LHP Kyle Hart elected free agency. |
| 11/02/25 | 2B Jose Iglesias elected free agency. |
| 11/02/25 | 1B Ryan O'Hearn elected free agency. |
| 11/02/25 | RHP Dylan Cease elected free agency. |
| 11/02/25 | 1B Luis Arraez elected free agency. |
| 11/02/25 | RHP Michael King elected free agency. |
| 11/02/25 | LHP Nestor Cortes elected free agency. |
| 11/02/25 | C Martín Maldonado elected free agency. |