Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 09/29/25 | St. Louis Cardinals activated SS Masyn Winn from the 10-day injured list. |
| 09/29/25 | St. Louis Cardinals activated 1B Willson Contreras from the 10-day injured list. |
| 09/29/25 | St. Louis Cardinals recalled LF Matt Koperniak from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled RHP Sem Robberse from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled 2B César Prieto from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled LHP Anthony Veneziano from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled RHP Tekoah Roby from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled LHP Nick Raquet from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled RHP Andre Granillo from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled RHP Tink Hence from Springfield Cardinals. |
| 09/29/25 | St. Louis Cardinals recalled CF Michael Siani from Memphis Redbirds. |
| 09/29/25 | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| 09/17/25 | St. Louis Cardinals placed 1B Willson Contreras on the 10-day injured list retroactive to September 16, 2025. Right shoulder strain. |
| 09/17/25 | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| 09/16/25 | 2B Brendan Donovan changed number to 33. |
| 09/15/25 | St. Louis Cardinals activated 3B Nolan Arenado from the 10-day injured list. |
| 09/15/25 | 2B Brendan Donovan changed number to 21. |
| 09/15/25 | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| 09/13/25 | St. Louis Cardinals placed SS Masyn Winn on the 10-day injured list. Torn meniscus in right knee. |
| 09/13/25 | St. Louis Cardinals recalled 2B José Fermín from Memphis Redbirds. |
| 09/12/25 | St. Louis Cardinals activated 2B Brendan Donovan from the 10-day injured list. |
| 09/12/25 | St. Louis Cardinals activated LHP John King from the 15-day injured list. |
| 09/12/25 | St. Louis Cardinals optioned LHP Nick Raquet to Memphis Redbirds. |
| 09/12/25 | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| 09/11/25 | St. Louis Cardinals released 2B Garrett Hampson. |
| 09/10/25 | St. Louis Cardinals sent LHP John King on a rehab assignment to Springfield Cardinals. |
| 09/10/25 | St. Louis Cardinals sent LHP John King on a rehab assignment to Springfield Cardinals. |
| 09/10/25 | St. Louis Cardinals sent 3B Nolan Arenado on a rehab assignment to Springfield Cardinals. |
| 09/09/25 | St. Louis Cardinals sent 2B Brendan Donovan on a rehab assignment to Springfield Cardinals. |
| 09/09/25 | St. Louis Cardinals activated 1B Willson Contreras. |
| 09/09/25 | St. Louis Cardinals sent 2B Brendan Donovan on a rehab assignment to Springfield Cardinals. |
| 09/08/25 | St. Louis Cardinals designated 2B Garrett Hampson for assignment. |
| 09/08/25 | St. Louis Cardinals activated 1B Alec Burleson from the 10-day injured list. |
| 09/08/25 | St. Louis Cardinals optioned RHP Andre Granillo to Memphis Redbirds. |
| 09/08/25 | St. Louis Cardinals selected the contract of LHP Nick Raquet from Memphis Redbirds. |
| 09/05/25 | St. Louis Cardinals activated C Yohel Pozo from the 7-day injured list. |
| 09/05/25 | 1B Willson Contreras suspended. |
| 09/05/25 | St. Louis Cardinals optioned 2B César Prieto to Memphis Redbirds. |
| 09/01/25 | St. Louis Cardinals activated CF Victor Scott II from the 10-day injured list. |
| 09/01/25 | St. Louis Cardinals recalled RHP Chris Roycroft from Memphis Redbirds. |