D-backs Roster & Staff
Transactions
| Date | Transaction |
| 12/23/22 | Arizona Diamondbacks activated SS Lourdes Gurriel Jr.. |
| 12/23/22 | Arizona Diamondbacks activated C Gabriel Moreno. |
| 12/23/22 | Arizona Diamondbacks activated SS Diego Castillo. |
| 12/23/22 | Arizona Diamondbacks activated SS Lourdes Gurriel Jr.. |
| 12/23/22 | Arizona Diamondbacks designated C Ali Sánchez for assignment. |
| 12/23/22 | Arizona Diamondbacks designated RHP Taylor Widener for assignment. |
| 12/23/22 | Pittsburgh Pirates traded SS Diego Castillo to Arizona Diamondbacks for RHP Scott Randall. |
| 12/23/22 | Pittsburgh Pirates traded SS Diego Castillo to Arizona Diamondbacks for RHP Scott Randall. |
| 12/23/22 | Arizona Diamondbacks traded C Daulton Varsho to Toronto Blue Jays for SS Lourdes Gurriel Jr. and C Gabriel Moreno. |
| 12/23/22 | Arizona Diamondbacks traded C Daulton Varsho to Toronto Blue Jays for SS Lourdes Gurriel Jr. and C Gabriel Moreno. |
| 12/23/22 | Arizona Diamondbacks traded C Daulton Varsho to Toronto Blue Jays for SS Lourdes Gurriel Jr. and C Gabriel Moreno. |
| 12/22/22 | Arizona Diamondbacks sent LHP Tyler Gilbert outright to Reno Aces. |
| 12/16/22 | Arizona Diamondbacks activated RHP Ryne Nelson. |
| 12/15/22 | Arizona Diamondbacks activated OF Jake McCarthy. |
| 12/15/22 | Arizona Diamondbacks signed free agent RHP Scott McGough. |
| 12/15/22 | Arizona Diamondbacks activated RHP Scott McGough. |
| 12/15/22 | Arizona Diamondbacks designated LHP Tyler Gilbert for assignment. |
| 12/14/22 | Arizona Diamondbacks signed free agent RHP Mervin Fell to a minor league contract. |
| 12/13/22 | Arizona Diamondbacks signed free agent RHP Boris Vecerka to a minor league contract. |
| 12/12/22 | LHP Sam Clay roster status changed by Arizona Diamondbacks. |
| 12/12/22 | LHP Sam Clay roster status changed by Arizona Diamondbacks. |
| 12/12/22 | Arizona Diamondbacks signed free agent LHP Sam Clay to a minor league contract. |
| 12/10/22 | Arizona Diamondbacks signed free agent SS Harlem Belen to a minor league contract. |
| 12/10/22 | Arizona Diamondbacks signed free agent RHP Jorge Minyety to a minor league contract. |
| 12/09/22 | Arizona Diamondbacks signed free agent RHP Zach McAllister to a minor league contract. |
| 12/09/22 | RHP Ryan Hendrix roster status changed by Arizona Diamondbacks. |
| 12/09/22 | RHP Tyler Ferguson roster status changed by Arizona Diamondbacks. |
| 12/09/22 | RHP Drey Jameson changed number to 27. |
| 12/09/22 | LHP Kyle Nelson changed number to 24. |
| 12/09/22 | Arizona Diamondbacks signed free agent RHP Ryan Hendrix to a minor league contract. |
| 12/09/22 | Arizona Diamondbacks signed free agent RHP Tyler Ferguson to a minor league contract. |
| 12/09/22 | RHP Tyler Ferguson roster status changed by Arizona Diamondbacks. |
| 12/09/22 | RHP Zach McAllister roster status changed by Arizona Diamondbacks. |
| 12/02/22 | Arizona Diamondbacks signed free agent RHP Miguel Castro. |
| 12/02/22 | Arizona Diamondbacks activated RHP Miguel Castro. |
| 12/02/22 | Arizona Diamondbacks claimed C Ali Sánchez off waivers from Pittsburgh Pirates. |
| 12/02/22 | San Diego Padres claimed RHP Sean Poppen off waivers from Arizona Diamondbacks. |
| 12/01/22 | Arizona Diamondbacks signed free agent RHP Austin Brice to a minor league contract. |
| 12/01/22 | RHP Austin Brice roster status changed by Arizona Diamondbacks. |