Orioles Roster & Staff
Transactions
| Date | Transaction |
| 04/23/25 | Baltimore Orioles sent LHP Trevor Rogers on a rehab assignment to Chesapeake Baysox. |
| 04/22/25 | Baltimore Orioles placed RHP Cody Poteet on the 15-day injured list retroactive to April 21, 2025. Right shoulder inflammation. |
| 04/22/25 | Baltimore Orioles recalled RHP Brandon Young from Norfolk Tides. |
| 04/20/25 | Baltimore Orioles traded RHP Scott Blewett to Atlanta Braves for cash. |
| 04/20/25 | Baltimore Orioles optioned RHP Brandon Young to Norfolk Tides. |
| 04/20/25 | Baltimore Orioles recalled RHP Cody Poteet from Norfolk Tides. |
| 04/19/25 | Baltimore Orioles designated RHP Scott Blewett for assignment. |
| 04/19/25 | Baltimore Orioles recalled RHP Brandon Young from Aberdeen IronBirds. |
| 04/16/25 | LHP Keegan Akin changed number to 45. |
| 04/16/25 | RHP Dean Kremer changed number to 64. |
| 04/16/25 | RHP Félix Bautista changed number to 74. |
| 04/16/25 | RHP Scott Blewett changed number to 67. |
| 04/16/25 | RHP Charlie Morton changed number to 50. |
| 04/16/25 | RHP Matt Bowman changed number to 51. |
| 04/16/25 | RF Ramón Laureano changed number to 12. |
| 04/16/25 | RHP Tomoyuki Sugano changed number to 19. |
| 04/16/25 | C Gary Sánchez changed number to 99. |
| 04/16/25 | LHP Gregory Soto changed number to 65. |
| 04/16/25 | 2B Jackson Holliday changed number to 7. |
| 04/16/25 | LF Tyler O'Neill changed number to 9. |
| 04/16/25 | RHP Seranthony Domínguez changed number to 56. |
| 04/16/25 | LHP Cade Povich changed number to 37. |
| 04/16/25 | LF Heston Kjerstad changed number to 13. |
| 04/16/25 | RHP Yennier Cano changed number to 78. |
| 04/16/25 | 3B Jordan Westburg changed number to 11. |
| 04/16/25 | C Adley Rutschman changed number to 35. |
| 04/16/25 | 1B Ryan O'Hearn changed number to 32. |
| 04/16/25 | SS Gunnar Henderson changed number to 2. |
| 04/16/25 | 3B Ramón Urías changed number to 29. |
| 04/16/25 | RHP Bryan Baker changed number to 43. |
| 04/16/25 | LHP Cionel Pérez changed number to 58. |
| 04/16/25 | 2B Jorge Mateo changed number to 3. |
| 04/16/25 | 1B Ryan Mountcastle changed number to 6. |
| 04/16/25 | CF Cedric Mullins changed number to 31. |
| 04/15/25 | 3B Jordan Westburg changed number to 42. |
| 04/15/25 | RHP Yennier Cano changed number to 42. |
| 04/15/25 | 1B Ryan O'Hearn changed number to 42. |
| 04/15/25 | C Adley Rutschman changed number to 42. |
| 04/15/25 | SS Gunnar Henderson changed number to 42. |
| 04/15/25 | 1B Ryan Mountcastle changed number to 42. |
| 04/15/25 | RHP Félix Bautista changed number to 42. |
| 04/15/25 | RHP Bryan Baker changed number to 42. |
| 04/15/25 | LHP Cionel Pérez changed number to 42. |
| 04/15/25 | 3B Ramón Urías changed number to 42. |
| 04/15/25 | RHP Dean Kremer changed number to 42. |
| 04/15/25 | CF Cedric Mullins changed number to 42. |
| 04/15/25 | LHP Keegan Akin changed number to 42. |
| 04/15/25 | Baltimore Orioles activated RHP Scott Blewett. |
| 04/15/25 | Baltimore Orioles released LHP Luis González. |
| 04/15/25 | 2B Jorge Mateo changed number to 42. |
| 04/15/25 | RHP Matt Bowman changed number to 42. |
| 04/15/25 | RHP Charlie Morton changed number to 42. |
| 04/15/25 | 2B Jackson Holliday changed number to 42. |
| 04/15/25 | LF Tyler O'Neill changed number to 42. |
| 04/15/25 | RHP Tomoyuki Sugano changed number to 42. |
| 04/15/25 | C Gary Sánchez changed number to 42. |
| 04/15/25 | LHP Gregory Soto changed number to 42. |
| 04/15/25 | RF Ramón Laureano changed number to 42. |
| 04/15/25 | LHP Cade Povich changed number to 42. |
| 04/15/25 | RHP Seranthony Domínguez changed number to 42. |
| 04/15/25 | LF Heston Kjerstad changed number to 42. |
| 04/15/25 | Baltimore Orioles optioned RHP Colin Selby to Norfolk Tides. |
| 04/14/25 | Baltimore Orioles designated LHP Luis González for assignment. |
| 04/14/25 | RHP Scott Blewett roster status changed by Baltimore Orioles. |
| 04/14/25 | Baltimore Orioles claimed RHP Scott Blewett off waivers from Minnesota Twins. |
| 04/13/25 | Baltimore Orioles signed free agent C Chadwick Tromp to a minor league contract. |
| 04/09/25 | Baltimore Orioles placed RHP Zach Eflin on the 15-day injured list retroactive to April 8, 2025. Right lat strain. |
| 04/09/25 | Baltimore Orioles activated RHP Colin Selby. |
| 04/09/25 | Baltimore Orioles recalled RHP Colin Selby from Norfolk Tides. |
| 04/07/25 | Baltimore Orioles transferred RHP Albert Suárez from the 15-day injured list to the 60-day injured list. Right subscapularis strain. |
| 04/07/25 | Baltimore Orioles traded LF Daz Cameron and cash to Milwaukee Brewers for LHP Grant Wolfram. |
| 04/07/25 | Baltimore Orioles traded LF Daz Cameron and cash to Milwaukee Brewers for LHP Grant Wolfram. |
| 04/07/25 | Baltimore Orioles optioned LHP Grant Wolfram to Norfolk Tides. |
| 04/05/25 | Baltimore Orioles traded 2B Nick Gordon to Kansas City Royals for cash. |
| 04/04/25 | Baltimore Orioles activated SS Gunnar Henderson from the 10-day injured list. |
| 04/04/25 | Baltimore Orioles optioned LF Dylan Carlson to Norfolk Tides. |