Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 03/31/18 | St. Louis Cardinals traded RHP Josh Lucas to Oakland Athletics for RHP Casey Meisner. |
| 03/31/18 | St. Louis Cardinals traded RHP Josh Lucas to Oakland Athletics for RHP Casey Meisner. |
| 03/31/18 | St. Louis Cardinals optioned RHP Greg Holland to Palm Beach Cardinals. |
| 03/31/18 | St. Louis Cardinals transferred RHP Alex Reyes from the 10-day disabled list to the 60-day disabled list. Right elbow injury. |
| 03/31/18 | St. Louis Cardinals signed free agent RHP Greg Holland. |
| 03/31/18 | St. Louis Cardinals recalled LHP Ryan Sherriff from Memphis Redbirds. |
| 03/31/18 | St. Louis Cardinals placed LHP Brett Cecil on the 10-day disabled list. Left shoulder strain. |
| 03/28/18 | St. Louis Cardinals selected the contract of C Francisco Pena from Memphis Redbirds. |
| 03/28/18 | St. Louis Cardinals designated 2B Breyvic Valera for assignment. |
| 03/28/18 | St. Louis Cardinals selected the contract of RHP Jordan Hicks from Springfield Cardinals. |
| 03/28/18 | St. Louis Cardinals placed RHP Adam Wainwright on the 10-day disabled list retroactive to March 26, 2018. Left hamstring strain, |
| 03/28/18 | St. Louis Cardinals designated RHP Josh Lucas for assignment. |
| 03/28/18 | St. Louis Cardinals recalled Jack Flaherty from Memphis Redbirds. |
| 03/28/18 | St. Louis Cardinals optioned RHP John Brebbia to Memphis Redbirds. |
| 03/28/18 | St. Louis Cardinals released RHP Joe Colon. |
| 03/28/18 | St. Louis Cardinals placed RHP Luke Gregerson on the 10-day disabled list retroactive to March 26, 2018. Left hamstring strain. |
| 03/28/18 | St. Louis Cardinals placed RHP Alex Reyes on the 10-day disabled list retroactive to March 26, 2018. Right elbow. |
| 03/25/18 | RHP Will Latcham assigned to St. Louis Cardinals. |
| 03/24/18 | LHP Austin Warner assigned to St. Louis Cardinals. |
| 03/23/18 | St. Louis Cardinals optioned CF Harrison Bader to Memphis Redbirds. |
| 03/23/18 | St. Louis Cardinals optioned RHP Josh Lucas to Memphis Redbirds. |
| 03/23/18 | St. Louis Cardinals optioned 1B Luke Voit to Memphis Redbirds. |
| 03/22/18 | St. Louis Cardinals released RHP Jason Motte. |
| 03/21/18 | RHP Austin Sexton assigned to St. Louis Cardinals. |
| 03/20/18 | LHP Jacob Evans assigned to St. Louis Cardinals. |
| 03/20/18 | LHP Ian McKinney assigned to St. Louis Cardinals. |
| 03/20/18 | RHP Thomas St. Clair assigned to St. Louis Cardinals. |
| 03/19/18 | St. Louis Cardinals optioned RHP John Gant to Memphis Redbirds. |
| 03/18/18 | St. Louis Cardinals optioned RHP Jack Flaherty to Memphis Redbirds. |
| 03/18/18 | St. Louis Cardinals optioned CF Oscar Mercado to Memphis Redbirds. |
| 03/18/18 | St. Louis Cardinals optioned LHP Ryan Sherriff to Memphis Redbirds. |
| 03/18/18 | St. Louis Cardinals optioned 2B Breyvic Valera to Memphis Redbirds. |
| 03/18/18 | St. Louis Cardinals optioned C Carson Kelly to Memphis Redbirds. |
| 03/18/18 | RHP Yeison Medina assigned to St. Louis Cardinals. |
| 03/17/18 | 2B Darren Seferina assigned to St. Louis Cardinals. |
| 03/16/18 | 2B Andy Young assigned to St. Louis Cardinals. |
| 03/16/18 | RF Dylan Carlson assigned to St. Louis Cardinals. |
| 03/16/18 | RF Thomas Spitz assigned to St. Louis Cardinals. |
| 03/16/18 | SS Kramer Robertson assigned to St. Louis Cardinals. |
| 03/16/18 | CF Terry Fuller assigned to St. Louis Cardinals. |
| 03/16/18 | C Julio Rodriguez assigned to St. Louis Cardinals. |
| 03/16/18 | 1B John Nogowski assigned to St. Louis Cardinals. |
| 03/16/18 | St. Louis Cardinals signed free agent LF Granden Goetzman to a minor league contract. |
| 03/16/18 | LHP Fabian Blanco assigned to St. Louis Cardinals. |
| 03/16/18 | LF Donivan Williams assigned to St. Louis Cardinals. |
| 03/16/18 | CF J.B. Woodman assigned to St. Louis Cardinals. |
| 03/16/18 | RHP Jake Walsh assigned to St. Louis Cardinals. |
| 03/16/18 | RHP Estarlin Arias assigned to St. Louis Cardinals. |
| 03/16/18 | LF Bryce Denton assigned to St. Louis Cardinals. |
| 03/16/18 | SS Ramon Urias assigned to St. Louis Cardinals. |
| 03/16/18 | C Brian O'Keefe assigned to St. Louis Cardinals. |
| 03/16/18 | RHP Joe Colon assigned to St. Louis Cardinals. |
| 03/15/18 | St. Louis Cardinals signed free agent RHP Nestor Molina to a minor league contract. |
| 03/15/18 | St. Louis Cardinals signed free agent RHP Edward Mujica to a minor league contract. |
| 03/15/18 | CF Lane Thomas assigned to St. Louis Cardinals. |
| 03/12/18 | St. Louis Cardinals optioned LHP Austin Gomber to Memphis Redbirds. |
| 03/12/18 | St. Louis Cardinals optioned SS Edmundo Sosa to Memphis Redbirds. |
| 03/12/18 | St. Louis Cardinals optioned RF Tyler O'Neill to Memphis Redbirds. |
| 03/12/18 | St. Louis Cardinals optioned RHP Derian Gonzalez to Springfield Cardinals. |
| 03/12/18 | St. Louis Cardinals optioned RHP Conner Greene to Springfield Cardinals. |
| 03/08/18 | IF Delvin Perez assigned to St. Louis Cardinals. |
| 03/07/18 | RHP Sam Tewes assigned to St. Louis Cardinals. |
| 03/07/18 | RHP Ramon Santos assigned to St. Louis Cardinals. |
| 03/06/18 | RHP Kevin Herget assigned to St. Louis Cardinals. |
| 03/06/18 | RHP Andrew Morales assigned to St. Louis Cardinals. |
| 03/06/18 | RHP Jesus Cruz assigned to St. Louis Cardinals. |
| 03/06/18 | RHP Matt Pearce assigned to St. Louis Cardinals. |
| 03/03/18 | RHP Connor Jones assigned to St. Louis Cardinals. |