Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 04/29/19 | St. Louis Cardinals activated RHP Michael Wacha from the 10-day injured list. |
| 04/29/19 | St. Louis Cardinals optioned RHP Ryan Helsley to Memphis Redbirds. |
| 04/26/19 | St. Louis Cardinals optioned CF Lane Thomas to Memphis Redbirds. |
| 04/26/19 | Tyler O'Neill roster status changed by St. Louis Cardinals. |
| 04/24/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Springfield Cardinals. |
| 04/24/19 | St. Louis Cardinals optioned RHP Daniel Ponce de Leon to Memphis Redbirds. |
| 04/24/19 | Harrison Bader roster status changed by St. Louis Cardinals. |
| 04/23/19 | St. Louis Cardinals recalled Daniel Ponce de Leon from Memphis Redbirds. |
| 04/23/19 | St. Louis Cardinals optioned 3B Drew Robinson to Memphis Redbirds. |
| 04/23/19 | St. Louis Cardinals sent LF Tyler O'Neill on a rehab assignment to Springfield Cardinals. |
| 04/22/19 | St. Louis Cardinals placed RHP Michael Wacha on the 10-day injured list retroactive to April 19, 2019. Left knee patellar tendinitis. |
| 04/22/19 | St. Louis Cardinals recalled Drew Robinson from Memphis Redbirds. |
| 04/19/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Memphis Redbirds. |
| 04/17/19 | St. Louis Cardinals signed free agent RHP Edgar Manzo to a minor league contract. |
| 04/17/19 | St. Louis Cardinals signed free agent SS Carlos Arcia to a minor league contract. |
| 04/17/19 | St. Louis Cardinals signed free agent RHP Wilmer Ortega to a minor league contract. |
| 04/17/19 | St. Louis Cardinals recalled Lane Thomas from Memphis Redbirds. |
| 04/17/19 | St. Louis Cardinals signed free agent C Roblin Heredia to a minor league contract. |
| 04/17/19 | St. Louis Cardinals placed CF Harrison Bader on the 10-day injured list retroactive to April 14, 2019. Right hamstring strain. |
| 04/17/19 | St. Louis Cardinals signed free agent CF Hansel Otamendi to a minor league contract. |
| 04/16/19 | St. Louis Cardinals recalled Ryan Helsley from Memphis Redbirds. |
| 04/16/19 | St. Louis Cardinals recalled RHP Giovanny Gallegos from Memphis Redbirds. |
| 04/16/19 | St. Louis Cardinals placed LF Tyler O'Neill on the 10-day injured list. Right elbow ulnar nerve subluxation. |
| 04/16/19 | St. Louis Cardinals placed RHP Mike Mayers on the 10-day injured list. Right shoulder lat strain. |
| 04/16/19 | St. Louis Cardinals optioned 3B Drew Robinson to Memphis Redbirds. |
| 04/16/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Springfield Cardinals. |
| 04/16/19 | St. Louis Cardinals recalled 2B Yairo Munoz from Memphis Redbirds. |
| 04/15/19 | St. Louis Cardinals optioned SS Yairo Munoz to Memphis Redbirds. |
| 04/15/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Palm Beach Cardinals. |
| 04/15/19 | St. Louis Cardinals optioned RHP Giovanny Gallegos to Memphis Redbirds. |
| 04/15/19 | St. Louis Cardinals recalled Drew Robinson from Memphis Redbirds. |
| 04/13/19 | St. Louis Cardinals recalled Yairo Munoz from Memphis Redbirds. |
| 04/12/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Springfield Cardinals. |
| 04/09/19 | RHP Chris Ellis returned to St. Louis Cardinals from Kansas City Royals. |
| 04/07/19 | St. Louis Cardinals optioned SS Yairo Munoz to Memphis Redbirds. |
| 04/07/19 | St. Louis Cardinals optioned RHP Alex Reyes to Memphis Redbirds. |
| 04/07/19 | St. Louis Cardinals recalled Giovanny Gallegos from Memphis Redbirds. |
| 04/07/19 | St. Louis Cardinals recalled Tyler Webb from Memphis Redbirds. |
| 04/05/19 | St. Louis Cardinals activated 3B Jedd Gyorko from the 10-day injured list. |
| 04/05/19 | St. Louis Cardinals optioned 3B Drew Robinson to Memphis Redbirds. |
| 04/04/19 | St. Louis Cardinals optioned 3B Drew Robinson to Memphis Redbirds. |
| 04/04/19 | St. Louis Cardinals sent RHP Luke Gregerson on a rehab assignment to Palm Beach Cardinals. |