Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 03/31/23 | St. Louis Cardinals traded LHP Anthony Misiewicz to Arizona Diamondbacks for cash. |
| 03/30/23 | St. Louis Cardinals placed SS Paul DeJong on the 10-day injured list retroactive to March 27, 2023. Back injury. |
| 03/30/23 | St. Louis Cardinals placed RHP Wilking Rodriguez on the 15-day injured list retroactive to March 27, 2023. Right shoulder injury. |
| 03/30/23 | St. Louis Cardinals signed free agent RHP Andrew Bolivar to a minor league contract. |
| 03/30/23 | St. Louis Cardinals placed RHP Adam Wainwright on the 15-day injured list retroactive to March 27, 2023. Groin injury. |
| 03/29/23 | St. Louis Cardinals designated LHP Anthony Misiewicz for assignment. |
| 03/29/23 | St. Louis Cardinals selected the contract of 3B Jordan Walker, , , and from Springfield Cardinals. |
| 03/27/23 | CF Tyler Reichenborn and assigned to St. Louis Cardinals. |
| 03/27/23 | RHP Jose Martinez and assigned to St. Louis Cardinals. |
| 03/27/23 | St. Louis Cardinals placed RHP Wilking Rodríguez on the 60-day injured list. |
| 03/26/23 | LHP Alex Cornwell and assigned to St. Louis Cardinals. |
| 03/25/23 | C Luis Rodriguez roster status changed by St. Louis Cardinals. |
| 03/25/23 | 2B Chandler Redmond and assigned to St. Louis Cardinals. |
| 03/25/23 | C Luis Rodriguez and assigned to St. Louis Cardinals. |
| 03/25/23 | C Luis Rodriguez and assigned to St. Louis Cardinals. |
| 03/25/23 | SS Arquímedes Gamboa and assigned to St. Louis Cardinals. |
| 03/25/23 | RHP Bryan Pope and assigned to St. Louis Cardinals. |
| 03/25/23 | St. Louis Cardinals optioned LHP Génesis Cabrera to Memphis Redbirds. |
| 03/25/23 | St. Louis Cardinals selected the contract of 2B Taylor Motter, , and from Memphis Redbirds. |
| 03/25/23 | St. Louis Cardinals optioned LHP JoJo Romero to Memphis Redbirds. |
| 03/25/23 | St. Louis Cardinals optioned 1B Juan Yepez to Memphis Redbirds. |
| 03/24/23 | St. Louis Cardinals signed free agent LHP Yadiel Batista to a minor league contract. |
| 03/24/23 | C Jose Zapata and assigned to St. Louis Cardinals. |
| 03/23/23 | St. Louis Cardinals optioned LHP Anthony Misiewicz to Memphis Redbirds. |
| 03/22/23 | RHP Brandon Komar and assigned to St. Louis Cardinals. |
| 03/22/23 | C Jake Burns and assigned to St. Louis Cardinals. |
| 03/21/23 | OF Todd Lott roster status changed by St. Louis Cardinals. |
| 03/21/23 | OF Todd Lott assigned to St. Louis Cardinals. |
| 03/21/23 | St. Louis Cardinals optioned LHP Matthew Liberatore to Memphis Redbirds. |
| 03/21/23 | St. Louis Cardinals optioned RHP Dakota Hudson to Memphis Redbirds. |
| 03/20/23 | 3B Osvaldo Tovalin and assigned to St. Louis Cardinals. |
| 03/20/23 | RHP Logan Gragg and assigned to St. Louis Cardinals. |
| 03/20/23 | RHP Dionys Rodriguez and assigned to St. Louis Cardinals. |
| 03/20/23 | C Carlos Linarez and assigned to St. Louis Cardinals. |
| 03/20/23 | RHP Hancel Rincon and assigned to St. Louis Cardinals. |
| 03/19/23 | LHP John Beller assigned to St. Louis Cardinals. |
| 03/19/23 | 3B Noah Mendlinger and assigned to St. Louis Cardinals. |
| 03/19/23 | LHP John Beller roster status changed by St. Louis Cardinals. |
| 03/18/23 | RHP Andrew Marrero and assigned to St. Louis Cardinals. |
| 03/18/23 | 2B Nick Dunn and assigned to St. Louis Cardinals. |
| 03/16/23 | SS Lizandro Espinoza and assigned to St. Louis Cardinals. |
| 03/16/23 | St. Louis Cardinals optioned C Iván Herrera to Memphis Redbirds. |
| 03/16/23 | St. Louis Cardinals optioned CF Moisés Gómez to Memphis Redbirds. |
| 03/16/23 | St. Louis Cardinals optioned LHP Connor Thomas to Memphis Redbirds. |
| 03/14/23 | Detroit Tigers claimed RHP Freddy Pacheco off waivers from St. Louis Cardinals. |
| 03/12/23 | OF Alex Iadisernia and assigned to St. Louis Cardinals. |
| 03/12/23 | 3B Jacob Buchberger and assigned to St. Louis Cardinals. |
| 03/12/23 | 3B Francisco Hernandez and assigned to St. Louis Cardinals. |
| 03/12/23 | SS Michael Curialle and assigned to St. Louis Cardinals. |
| 03/11/23 | OF Chris Rotondo and assigned to St. Louis Cardinals. |
| 03/11/23 | OF Won-Bin Cho and assigned to St. Louis Cardinals. |
| 03/11/23 | SS R.J. Yeager and assigned to St. Louis Cardinals. |
| 03/11/23 | St. Louis Cardinals optioned RHP Jake Walsh to Memphis Redbirds. |
| 03/11/23 | St. Louis Cardinals optioned SS Jose Fermin to Memphis Redbirds. |
| 03/10/23 | OF Joshua Baez and assigned to St. Louis Cardinals. |
| 03/10/23 | 2B Irving Lopez and assigned to St. Louis Cardinals. |
| 03/10/23 | OF Justin Toerner and assigned to St. Louis Cardinals. |
| 03/07/23 | SS Brody Moore and assigned to St. Louis Cardinals. |
| 03/04/23 | SS Errol Robinson assigned to St. Louis Cardinals. |
| 03/04/23 | SS Errol Robinson roster status changed by St. Louis Cardinals. |
| 03/04/23 | St. Louis Cardinals optioned RHP Freddy Pacheco to Memphis Redbirds. |
| 03/04/23 | St. Louis Cardinals optioned RHP Guillermo Zuñiga to Memphis Redbirds. |