Giants Roster & Staff
Transactions
| Date | Transaction |
| 11/30/21 | San Francisco Giants activated RHP Alex Cobb. |
| 11/30/21 | LHP Joe Palumbo elected free agency. |
| 11/30/21 | San Francisco Giants signed free agent RHP Alex Cobb. |
| 11/30/21 | San Francisco Giants activated RHP Alex Cobb. |
| 11/30/21 | OF Luis Gonzalez elected free agency. |
| 11/30/21 | 2B Alex Blandino roster status changed by San Francisco Giants. |
| 11/30/21 | San Francisco Giants signed free agent 2B Alex Blandino to a minor league contract and invited him to spring training. |
| 11/30/21 | RHP Sam Delaplane elected free agency. |
| 11/28/21 | San Francisco Giants signed free agent RHP Trevor Hildenberger to a minor league contract. |
| 11/24/21 | San Francisco Giants released LF Alex Dickerson. |
| 11/23/21 | San Francisco Giants designated LF Alex Dickerson for assignment. |
| 11/22/21 | San Francisco Giants signed free agent RHP Anthony DeSclafani, and. |
| 11/22/21 | San Francisco Giants traded RHP Jay Jackson to Atlanta Braves for Player To Be Named Later. |
| 11/19/21 | San Francisco Giants designated RHP Jay Jackson for assignment. |
| 11/19/21 | San Francisco Giants selected the contract of RHP Randy Rodriguez from San Jose Giants. |
| 11/19/21 | San Francisco Giants selected the contract of OF Heliot Ramos from Sacramento River Cats. |
| 11/19/21 | San Francisco Giants selected the contract of RHP Sean Hjelle from Sacramento River Cats. |
| 11/19/21 | RHP Dedniel Nunez returned to New York Mets from San Francisco Giants. |
| 11/18/21 | San Francisco Giants signed free agent RHP Peter Tago to a minor league contract and invited him to spring training. |
| 11/18/21 | RHP Peter Tago roster status changed by San Francisco Giants. |
| 11/17/21 | San Francisco Giants signed free agent 1B Brandon Belt. |
| 11/11/21 | San Francisco Giants signed free agent RHP Melvin Pineda to a minor league contract. |
| 11/07/21 | San Francisco Giants activated RHP Tyler Beede from the 60-day injured list. |
| 11/07/21 | San Francisco Giants activated OF Luis Gonzalez from the 60-day injured list. |
| 11/07/21 | San Francisco Giants activated RHP Sam Delaplane. |
| 11/07/21 | San Francisco Giants activated RHP Dedniel Nunez from the 60-day injured list. |
| 11/07/21 | San Francisco Giants activated RHP Tyler Beede from the 60-day injured list. |
| 11/07/21 | San Francisco Giants selected the contract of RHP Yunior Marte from Sacramento River Cats. |
| 11/07/21 | San Francisco Giants activated RHP Tyler Beede from the 60-day injured list. |
| 11/05/21 | RHP Johnny Cueto elected free agency. |
| 11/05/21 | San Francisco Giants claimed RHP Hunter Harvey off waivers from Baltimore Orioles. |
| 11/05/21 | San Francisco Giants claimed LF Austin Dean off waivers from St. Louis Cardinals. |
| 11/05/21 | San Francisco Giants claimed LHP Joe Palumbo off waivers from Texas Rangers. |
| 11/04/21 | C Buster Posey retired. |
| 11/03/21 | LHP Alex Wood elected free agency. |
| 11/03/21 | RHP Tyler Chatwood elected free agency. |
| 11/03/21 | 3B Kris Bryant elected free agency. |
| 11/03/21 | 1B Brandon Belt elected free agency. |
| 11/03/21 | LHP Tony Watson elected free agency. |
| 11/03/21 | LHP Scott Kazmir elected free agency. |
| 11/03/21 | 2B Donovan Solano elected free agency. |
| 11/03/21 | RHP Anthony DeSclafani elected free agency. |
| 11/03/21 | RHP Kevin Gausman elected free agency. |