Giants Roster & Staff
Transactions
| Date | Transaction |
| 05/31/22 | San Francisco Giants placed 1B Darin Ruf on the bereavement list. |
| 05/31/22 | San Francisco Giants recalled OF Heliot Ramos from Sacramento River Cats. |
| 05/28/22 | San Francisco Giants activated C Curt Casali from the 7-day injured list. |
| 05/28/22 | San Francisco Giants optioned C Michael Papierski to Sacramento River Cats. |
| 05/27/22 | San Francisco Giants activated LHP Jake McGee. |
| 05/26/22 | San Francisco Giants optioned RHP Mauricio Llovera to Sacramento River Cats. |
| 05/25/22 | San Francisco Giants optioned 3B Kevin Padlo to Sacramento River Cats. |
| 05/25/22 | San Francisco Giants recalled 2B Donovan Walton from Sacramento River Cats. |
| 05/24/22 | San Francisco Giants signed free agent 2B Riley Mahan to a minor league contract. |
| 05/23/22 | San Francisco Giants placed LF Austin Slater on the 10-day injured list. Left wrist inflammation. |
| 05/23/22 | San Francisco Giants recalled OF Stuart Fairchild from Sacramento River Cats. |
| 05/22/22 | San Francisco Giants placed 1B Brandon Belt on the 10-day injured list retroactive to May 19, 2022. Right knee inflammation. |
| 05/22/22 | San Francisco Giants recalled 3B Kevin Padlo from Sacramento River Cats. |
| 05/21/22 | San Francisco Giants placed C Curt Casali on the 7-day injured list. Concussion. |
| 05/21/22 | San Francisco Giants designated 3B Luke Williams for assignment. |
| 05/21/22 | San Francisco Giants selected the contract of C Michael Papierski from Sacramento River Cats. |
| 05/20/22 | San Francisco Giants recalled OF Luis Gonzalez from Sacramento River Cats. |
| 05/19/22 | San Francisco Giants placed CF LaMonte Wade Jr. on the 10-day injured list. Left knee inflammation. |
| 05/18/22 | San Francisco Giants sent LHP Jake McGee on a rehab assignment to Sacramento River Cats. |
| 05/16/22 | San Francisco Giants activated 2B Tommy La Stella. |
| 05/16/22 | San Francisco Giants activated 2B Tommy La Stella. |
| 05/16/22 | San Francisco Giants signed free agent RHP Spencer Bivens to a minor league contract. |
| 05/16/22 | San Francisco Giants transferred RHP Anthony DeSclafani from the 10-day injured list to the 60-day injured list. Right ankle inflammation. |
| 05/16/22 | San Francisco Giants selected the contract of RHP Mauricio Llovera from Sacramento River Cats. |
| 05/16/22 | San Francisco Giants optioned OF Luis Gonzalez to Sacramento River Cats. |
| 05/16/22 | San Francisco Giants optioned RHP Yunior Marte to Sacramento River Cats. |
| 05/15/22 | San Francisco Giants recalled RHP Yunior Marte from Sacramento River Cats. |
| 05/15/22 | San Francisco Giants optioned 2B Donovan Walton to Sacramento River Cats. |
| 05/14/22 | San Francisco Giants traded SS Mauricio Dubon to Houston Astros for C Michael Papierski. |
| 05/14/22 | San Francisco Giants traded SS Mauricio Dubon to Houston Astros for C Michael Papierski. |
| 05/14/22 | San Francisco Giants recalled 2B Donovan Walton from Sacramento River Cats. |
| 05/14/22 | San Francisco Giants optioned OF Stuart Fairchild to Sacramento River Cats. |
| 05/14/22 | Seattle Mariners traded OF Stuart Fairchild to San Francisco Giants for 2B Alex Blandino and cash. |
| 05/14/22 | Seattle Mariners traded OF Stuart Fairchild to San Francisco Giants for 2B Alex Blandino and cash. |
| 05/12/22 | San Francisco Giants traded 1B Mike Ford to Seattle Mariners for cash. |
| 05/12/22 | Pittsburgh Pirates claimed RHP Tyler Beede off waivers from San Francisco Giants. |
| 05/11/22 | San Francisco Giants activated 3B Evan Longoria. |
| 05/11/22 | San Francisco Giants designated 1B Mike Ford for assignment. |
| 05/11/22 | San Francisco Giants placed LHP Jake McGee on the 15-day injured list. Lower back tightness. |
| 05/11/22 | San Francisco Giants traded RHP Prelander Berroa to Seattle Mariners for 2B Donovan Walton. |
| 05/11/22 | San Francisco Giants traded RHP Prelander Berroa to Seattle Mariners for 2B Donovan Walton. |
| 05/11/22 | San Francisco Giants optioned 2B Donovan Walton to Sacramento River Cats. |
| 05/08/22 | San Francisco Giants optioned RHP Gregory Santos to Sacramento River Cats. |
| 05/08/22 | San Francisco Giants recalled RHP Jakob Junis from Sacramento River Cats. |
| 05/08/22 | San Francisco Giants traded RHP Corey Oswalt to Philadelphia Phillies. |
| 05/07/22 | San Francisco Giants activated RHP Dominic Leone from the 10-day injured list. |
| 05/07/22 | San Francisco Giants activated 1B Brandon Belt from the 10-day injured list. |
| 05/07/22 | San Francisco Giants optioned 3B Jason Vosler to Sacramento River Cats. |
| 05/07/22 | San Francisco Giants optioned RHP Sean Hjelle to Sacramento River Cats. |
| 05/06/22 | San Francisco Giants activated CF LaMonte Wade Jr.. |
| 05/06/22 | San Francisco Giants recalled RHP Sean Hjelle from Sacramento River Cats. |
| 05/06/22 | San Francisco Giants optioned LHP Sam Long to Sacramento River Cats. |
| 05/06/22 | San Francisco Giants optioned RHP Mauricio Llovera to Sacramento River Cats. |
| 05/05/22 | San Francisco Giants activated RHP Zack Littell from the 10-day injured list. |
| 05/05/22 | San Francisco Giants designated RHP Tyler Beede for assignment. |
| 05/05/22 | San Francisco Giants recalled RHP Gregory Santos from Sacramento River Cats. |
| 05/05/22 | San Francisco Giants optioned 3B Kevin Padlo to Sacramento River Cats. |
| 05/04/22 | San Francisco Giants signed free agent LHP Darien Nunez to a minor league contract. |
| 05/04/22 | San Francisco Giants activated RF Mike Yastrzemski from the 10-day injured list. |
| 05/04/22 | San Francisco Giants optioned 3B Luke Williams to Sacramento River Cats. |
| 05/04/22 | San Francisco Giants sent LF Jason Krizan outright to Sacramento River Cats. |
| 05/04/22 | Washington Nationals claimed RHP Cory Abbott off waivers from San Francisco Giants. |
| 05/03/22 | San Francisco Giants signed free agent LHP Scott Alexander to a minor league contract. |
| 05/03/22 | San Francisco Giants sent 2B Tommy La Stella on a rehab assignment to Sacramento River Cats. |
| 05/03/22 | San Francisco Giants sent 3B Evan Longoria on a rehab assignment to Sacramento River Cats. |
| 05/03/22 | San Francisco Giants optioned 1B Mike Ford to Sacramento River Cats. |
| 05/03/22 | San Francisco Giants recalled 3B Kevin Padlo from Sacramento River Cats. |
| 05/02/22 | San Francisco Giants optioned RHP Yunior Marte to Sacramento River Cats. |
| 05/02/22 | San Francisco Giants optioned LF Jason Krizan to Sacramento River Cats. |
| 05/01/22 | San Francisco Giants activated RHP Alex Cobb from the 10-day injured list. |
| 05/01/22 | San Francisco Giants optioned RHP Kervin Castro to Sacramento River Cats. |