Giants Roster & Staff
Transactions
| Date | Transaction |
| 05/31/10 | Ryan Rohlinger roster status changed by San Francisco Giants. |
| 05/31/10 | San Francisco Giants recalled Matt Downs from Fresno Grizzlies. |
| 05/30/10 | Pat Burrell assigned to Fresno Grizzlies from San Francisco Giants. |
| 05/29/10 | San Francisco Giants signed free agent LF Pat Burrell to a minor league contract. |
| 05/29/10 | San Francisco Giants optioned RHP Waldis Joaquin to Fresno Grizzlies. |
| 05/29/10 | San Francisco Giants recalled Buster Posey from Fresno Grizzlies. |
| 05/27/10 | San Francisco Giants recalled Waldis Joaquin from Fresno Grizzlies. |
| 05/27/10 | San Francisco Giants recalled Ryan Rohlinger from Fresno Grizzlies. |
| 05/27/10 | San Francisco Giants optioned Matt Downs to Fresno Grizzlies. |
| 05/26/10 | San Francisco Giants placed SS Edgar Renteria on the 15-day disabled list. Strained Right Hamstring |
| 05/22/10 | San Francisco Giants activated SS Edgar Renteria from the 15-day disabled list. |
| 05/22/10 | San Francisco Giants optioned 3B Ryan Rohlinger to Fresno Grizzlies. |
| 05/21/10 | Brandon Medders roster status changed by San Francisco Giants. |
| 05/21/10 | Emmanuel Burriss roster status changed by San Francisco Giants. |
| 05/21/10 | San Francisco Giants purchased RHP Santiago Casilla from Fresno Grizzlies. |
| 05/19/10 | San Francisco Giants optioned Eugenio Velez to Fresno Grizzlies. |
| 05/19/10 | San Francisco Giants activated 2B Freddy Sanchez from the 15-day disabled list. |
| 05/17/10 | San Francisco Giants placed LF Mark DeRosa on the 15-day disabled list. Left Wrist Injury |
| 05/17/10 | San Francisco Giants recalled Eugenio Velez from Fresno Grizzlies. |
| 05/17/10 | Eugenio Velez roster status changed by San Francisco Giants. |
| 05/10/10 | Wilmin Rodriguez assigned to Richmond Flying Squirrels from San Francisco Giants. |
| 05/09/10 | RHP Brian Anderson assigned to San Jose Giants from San Francisco Giants. |
| 05/07/10 | San Francisco Giants recalled Ryan Rohlinger from Fresno Grizzlies. |
| 05/07/10 | San Francisco Giants optioned LF Eugenio Velez to Fresno Grizzlies. |
| 05/07/10 | San Francisco Giants placed SS Edgar Renteria on the 15-day disabled list. Right groin strain. |
| 05/07/10 | San Francisco Giants selected the contract of RHP Denny Bautista from Fresno Grizzlies. |
| 05/02/10 | San Francisco Giants optioned Waldis Joaquin to Fresno Grizzlies. |
| 05/02/10 | San Francisco Giants activated CF Aaron Rowand from the 15-day disabled list. |
| 05/01/10 | San Francisco Giants signed free agent C Fernando Pujadas to a minor league contract. |
| 05/01/10 | San Francisco Giants signed free agent RHP Juan Nova to a minor league contract. |