The Pinstripe Bowl’s debut on December 30th, 2010, marked the first college bowl game at Yankee Stadium since the Gotham Bowl in 1962. The inaugural game saw Syracuse defeat Kansas State, 36-34. In 2014, the Pinstripe Bowl realigned and partnered with the Atlantic Coast Conference and Big Ten Conference, and has brought teams such as Penn State, Nebraska, Miami (Fla.), Wisconsin, Duke, Indiana, Boston College, and Rutgers to Yankee Stadium. Many Pinstripe Bowl alumni have gone on to have success in the NFL, including Zack Martin, Jonathan Taylor, Mohamed Sanu, Justin Pugh, Logan Ryan, Tavon Austin, and Kyle Monangai, among others.



Since 1923, Yankee Stadium has hosted some of the most memorable games the sport has seen. Dating back to Syracuse's 3-0 victory over Pittsburgh on October 20, 1923, the original Yankee Stadium hosted 185 collegiate football games. Notable contests included the 1946 scoreless tie between second-ranked Notre Dame and top-ranked Army, considered to be “The Game of the Century," along with Notre Dame's 12-6 win over Army on November 10, 1928, inspired by Coach Knute Rockne's "Win One for the Gipper" speech. In 2010, Notre Dame and Army returned to the Bronx to play the first football game at the current Yankee Stadium. The Fighting Irish and Black Knights met again at Yankee Stadium in 2024—nationally ranked No. 6 and No. 19, respectively—for Notre Dame’s annual Shamrock Series game. Since 2010, Yankee Stadium has hosted 10 regular season college football games, including the 150th meeting between longstanding rivals Lehigh and Lafayette, the 63rd annual Cortaca Jug game played between Ithaca College and SUNY Cortland, and the 100th anniversary of the inaugural game at the original Yankee Stadium between Syracuse and Pittsburgh.