Orioles Roster & Staff
Transactions
| Date | Transaction |
| 06/27/10 | Baltimore Orioles activated RHP Koji Uehara from the 15-day disabled list. |
| 06/27/10 | Baltimore Orioles designated 1B Garrett Atkins for assignment. |
| 06/26/10 | Baltimore Orioles recalled Brad Bergesen from Norfolk Tides. |
| 06/25/10 | C Tanner Murphy assigned to GCL Orioles from Baltimore Orioles. |
| 06/25/10 | OF Marcus Jones assigned to GCL Orioles from Baltimore Orioles. |
| 06/25/10 | Trent Mummey assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/25/10 | C Joe Velleggia assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/25/10 | OF Chris Clinton assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/25/10 | Riley Hornback assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/25/10 | RHP Travis Strong assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/25/10 | LHP Cameron Roth assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/24/10 | Baltimore Orioles signed LHP Cameron Roth. |
| 06/24/10 | Baltimore Orioles signed RHP Travis Strong. |
| 06/24/10 | Baltimore Orioles signed OF Chris Clinton. |
| 06/24/10 | Baltimore Orioles signed C Tanner Murphy. |
| 06/24/10 | Baltimore Orioles signed free agent OF Marcus Jones to a minor league contract. |
| 06/24/10 | Baltimore Orioles signed C Riley Hornback. |
| 06/24/10 | Baltimore Orioles signed C Joe Velleggia. |
| 06/24/10 | Baltimore Orioles signed OF Trent Mummey. |
| 06/23/10 | OF Jeremy Shelby assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Jake Pettit assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | 3B Brad Decater assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Steven Mazur assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Baltimore Orioles signed OF Jeremy Shelby. |
| 06/22/10 | OF Cody Young assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Vincent Zazueta assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Michael Mosby assigned to Bluefield Orioles from Baltimore Orioles. |
| 06/22/10 | Baltimore Orioles designated Cla Meredith for assignment. |
| 06/22/10 | Oakland Athletics Traded C Jake Fox to Baltimore Orioles and Norfolk Tides Traded RHP Ross Wolf to Sacramento River Cats. |
| 06/22/10 | Baltimore Orioles optioned Chris Tillman to Norfolk Tides. |
| 06/21/10 | LHP Chris Lamb assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | RHP David Richardson assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Aaron Swenson assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Baltimore Orioles placed LF Luis Montanez on the 15-day disabled list. strained left oblique |
| 06/21/10 | RHP Derek Hanks assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Baltimore Orioles signed Michael Mosby. |
| 06/21/10 | Baltimore Orioles signed OF Cody Young. |
| 06/21/10 | Baltimore Orioles signed SS Brad Decater. |
| 06/21/10 | Baltimore Orioles signed LHP Jake Pettit. |
| 06/21/10 | Baltimore Orioles signed RHP Steven Mazur. |
| 06/21/10 | OF Preston Hale assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Chris Petrini assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Tim Berry assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Andy Deain assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | D.J. Ferguson assigned to GCL Orioles from Baltimore Orioles. |
| 06/21/10 | Baltimore Orioles signed SS Vincent Zazueta. |
| 06/20/10 | Baltimore Orioles signed free agent RHP D.J. Ferguson to a minor league contract. |
| 06/20/10 | Baltimore Orioles signed free agent RHP Derek Hanks to a minor league contract. |
| 06/20/10 | Baltimore Orioles signed free agent RHP Andy Deain to a minor league contract. |
| 06/20/10 | Baltimore Orioles signed 1B Preston Hale. |
| 06/20/10 | Baltimore Orioles signed free agent LHP Chris Lamb to a minor league contract. |
| 06/20/10 | Baltimore Orioles signed RHP David Richardson. |
| 06/20/10 | Baltimore Orioles signed free agent RHP Aaron Swenson to a minor league contract. |
| 06/20/10 | Baltimore Orioles signed free agent LHP Chris Petrini to a minor league contract. |
| 06/17/10 | Joe Oliveira assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Auburn Donaldson assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Adam Gaylord assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Austin Goolsby assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Jeremy Nowak assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Scott Copeland assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Timothy Adleman assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Michael Rooney assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | Austin Knight assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/17/10 | SS Sammie Starr assigned to Aberdeen IronBirds from Baltimore Orioles. |
| 06/16/10 | Baltimore Orioles signed RHP Timothy Adleman. |
| 06/16/10 | Baltimore Orioles signed SS Michael Rooney. |
| 06/16/10 | Baltimore Orioles signed 3B Adam Gaylord. |
| 06/16/10 | Baltimore Orioles signed IF Auburn Donaldson. |
| 06/16/10 | Baltimore Orioles signed C Joe Oliveira. |
| 06/16/10 | Baltimore Orioles signed C Austin Goolsby. |
| 06/16/10 | Baltimore Orioles signed RHP Scott Copeland. |
| 06/16/10 | Baltimore Orioles signed SS Sammie Starr. |
| 06/16/10 | Baltimore Orioles signed OF Austin Knight. |
| 06/16/10 | Baltimore Orioles signed OF Jeremy Nowak. |
| 06/14/10 | Baltimore Orioles optioned Brad Bergesen to Norfolk Tides. |
| 06/14/10 | Baltimore Orioles activated RHP Alfredo Simon from the 15-day disabled list. |
| 06/14/10 | Baltimore Orioles signed 3B Michael Mosby. |
| 06/11/10 | Baltimore Orioles sent LHP Alberto Castillo outright to Norfolk Tides. |
| 06/10/10 | Baltimore Orioles selected the contract of RHP Jake Arrieta from Norfolk Tides. |
| 06/10/10 | Baltimore Orioles designated LHP Alberto Castillo for assignment. |