Orioles Roster & Staff
Transactions
| Date | Transaction |
| 07/30/22 | Baltimore Orioles signed RHP Zack Showalter. |
| 07/29/22 | Baltimore Orioles activated RHP Kyle Bradish from the 15-day injured list. |
| 07/29/22 | Baltimore Orioles optioned RHP Logan Gillaspie to Norfolk Tides. |
| 07/28/22 | Baltimore Orioles placed RHP Tyler Wells on the 15-day injured list. Lower left side discomfort. |
| 07/28/22 | Baltimore Orioles recalled RHP Beau Sulser from Norfolk Tides. |
| 07/28/22 | Baltimore Orioles optioned LHP Nick Vespi to Norfolk Tides. |
| 07/28/22 | Baltimore Orioles recalled RHP Logan Gillaspie from Norfolk Tides. |
| 07/27/22 | Baltimore Orioles signed SS Jackson Holliday. |
| 07/26/22 | Baltimore Orioles signed C Adam Retzbach. |
| 07/26/22 | Baltimore Orioles signed OF Douglas Hodo III. |
| 07/26/22 | Baltimore Orioles signed RHP Trace Bright. |
| 07/26/22 | Baltimore Orioles signed 3B Max Wagner. |
| 07/26/22 | Baltimore Orioles signed RHP Preston Johnson. |
| 07/26/22 | Baltimore Orioles signed C Silas Ardoin. |
| 07/26/22 | Baltimore Orioles signed RHP Cameron Weston. |
| 07/26/22 | Baltimore Orioles signed RHP Bradley Brehmer. |
| 07/26/22 | Baltimore Orioles placed SS Jonathan Arauz on the 10-day injured list. Right digit avulsion fracture. |
| 07/26/22 | Baltimore Orioles signed free agent 1B Maxwell Costes to a minor league contract. |
| 07/26/22 | Baltimore Orioles signed SS Adam Crampton. |
| 07/26/22 | Baltimore Orioles signed LHP Jared Beck. |
| 07/26/22 | Baltimore Orioles signed RHP Reese Sharp. |
| 07/26/22 | Baltimore Orioles signed RHP Wyatt Cheney. |
| 07/26/22 | Baltimore Orioles signed RHP Graham Firoved. |
| 07/26/22 | Baltimore Orioles recalled SS Terrin Vavra from Norfolk Tides. |
| 07/25/22 | Baltimore Orioles optioned RHP Rico Garcia to Norfolk Tides. |
| 07/25/22 | Baltimore Orioles recalled LHP Nick Vespi from Norfolk Tides. |
| 07/24/22 | Baltimore Orioles sent RHP Kyle Bradish on a rehab assignment to Norfolk Tides. |
| 07/23/22 | Baltimore Orioles signed OF Jud Fabian. |
| 07/23/22 | Baltimore Orioles signed OF Dylan Beavers. |
| 07/15/22 | Baltimore Orioles signed free agent RHP Carson King to a minor league contract. |
| 07/14/22 | Cleveland Guardians claimed LHP Kirk McCarty off waivers from Baltimore Orioles. |
| 07/12/22 | Baltimore Orioles designated LHP Kirk McCarty for assignment. |
| 07/12/22 | Baltimore Orioles claimed RHP Louis Head off waivers from Miami Marlins. |
| 07/11/22 | Baltimore Orioles sent RHP Travis Lakins Sr. on a rehab assignment to FCL Orioles. |
| 07/11/22 | Baltimore Orioles sent RHP Travis Lakins Sr. on a rehab assignment to FCL Orioles. |
| 07/11/22 | Baltimore Orioles traded RHP Cody Sedlock to Detroit Tigers. |
| 07/10/22 | Baltimore Orioles transferred RHP Travis Lakins Sr. from the 15-day injured list to the 60-day injured list. Right elbow inflammation. |
| 07/10/22 | Baltimore Orioles sent RHP Marcos Diplan outright to Norfolk Tides. |
| 07/10/22 | Baltimore Orioles selected the contract of RHP Rico Garcia from Norfolk Tides. |
| 07/10/22 | Baltimore Orioles optioned LHP Bruce Zimmermann to Norfolk Tides. |
| 07/09/22 | Baltimore Orioles sent RHP Kyle Bradish on a rehab assignment to Bowie Baysox. |
| 07/09/22 | Baltimore Orioles optioned RHP Beau Sulser to Norfolk Tides. |
| 07/09/22 | Baltimore Orioles recalled LHP Bruce Zimmermann from Norfolk Tides. |
| 07/06/22 | Baltimore Orioles designated RHP Marcos Diplan for assignment. |
| 07/06/22 | Baltimore Orioles optioned LHP Nick Vespi to Norfolk Tides. |
| 07/06/22 | Baltimore Orioles recalled RHP Beau Sulser from Norfolk Tides. |
| 07/06/22 | Baltimore Orioles claimed LHP Kirk McCarty off waivers from Cleveland Guardians. |
| 07/06/22 | Baltimore Orioles optioned LHP Kirk McCarty to Norfolk Tides. |
| 07/04/22 | Baltimore Orioles activated 2B Ramon Urias. |
| 07/04/22 | Baltimore Orioles signed free agent RHP Geronimo Rombley to a minor league contract. |
| 07/04/22 | Baltimore Orioles optioned SS Richie Martin to Norfolk Tides. |
| 07/02/22 | Baltimore Orioles sent 2B Ramon Urias on a rehab assignment to Bowie Baysox. |